BioTime Inc. (NYSE:BTX) said today that it expanded its OpRegen Phase I/IIa trial into the U.S. with 2 new trial sites. The company’s study is evaluating its OpRegen cell therapy in patients with advanced dry form age-related macular degeneration. The 2 U.S.-based trial sites will include ophthalmologists Dr. David Boyer from the Retina-Vitreous Associates Medical Group […]
Stem Cells
Stem cell transplants could improve insulin independence in T1D
Researchers from the City of Hope demonstrated that some patients with Type I diabetes can be cured, at least temporarily, with a stem cell transplant. The team’s work was published in Frontiers in Immunology. The trial enrolled 21 patients and found that autologous hematopoietic stem cell transplantation increased C-peptide levels and induced insulin independence in patients with […]
InGeneron raises $20m in Series D for regenerative stem cell therapies
InGeneron said today that healthcare provider Sanford Health invested $20 million in the company’s Series D financing round. The Houston, Texas.-based company said the funding will be used to support the clinical programs for its stem cell injections in patients with rotator cuff and venous ulcer tears. “This significant investment demonstrates Sanford’s commitment to be […]
Research shows stem cell treatment could improve irregular heartbeat
A study published in Stem Cells Translational Medicine showed that treating heart patients with mesenchymal stem cells does not increase their risk for irregular heart beat and instead improved the patients’ cardiac conditions. Previous studies have shown that stem cells have the potential to repair the damage caused by heart disease, but there was speculation that some […]
BrainStorm seeks early Health Canada nod for NurOwn treatment
Brainstorm Cell Therapeutics (NSDQ:BCLI) is reportedly seeking early regulatory approval in Canada for its NurOwn stem cell treatment for patients with ALS. The company told Reuters this week that it has inked an agreement with a Canadian non-profit organization, CCRM, that helps to support the development of regenerative medicine. The organization plans to help BrainStorm meet Canadian regulatory requirements […]
TiGenix, Takeda highlight data for cell therapy in patients with Chron’s disease
Takeda (TYO:4502) and TiGenix (EBR:TIG) today touted long-term data from its phase III Admire-CD trial evaluating its suspension of allogenic expanded adipose-derived stem cells, Cx601, in patients with Chron’s disease. The study showed that Cx601 maintained long-term remission of treatment refractory complex perianal fistulas over 52 weeks. The randomized, phase III trial compared Cx601 to […]
Orthocell, J&J’s DePuy Synthes ink R&D deal for stem cell treatment
Orthocell (ASX:OCC) said today that it landed a research collaboration deal with Johnson & Johnson (NYSE:JNJ) subsidiary DePuy Synthes for its Ortho-ATI stem cell regenerative therapy. The 2 groups are planning a collaborative study for the 1st quarter in 2017, led by Allan Wang from the University of Western Australia. In previous studies, Ortho-ATI has proven […]
Study shows Alzheimer’s drug activates stem cells in teeth
Researchers from King’s College London have shown that an Alzheimer’s drug can stimulate the stem cells found in tooth pulp and generate a protective material, dentine, in large cavities. The team’s work was published yesterday in Scientific Reports. If the soft pulp of a tooth becomes infected after a traumatic event, a thin layer of dentine is […]
Frequency Therapeutics names board of directors
Frequency Therapeutics named its board of directors last week, the company’s 1st public move since it was founded in 2015. Marc Cohen of COBRO Ventures was named chairman. Founder and former CEO of Sepracor, Inc., joined the board as well as Marc Kozin, senior advisor and former president of L.E.K. Consulting. Robert Langer, who co-founded […]
Scientists develop silver-releasing scaffold to prevent MRSA infection in bone
Researchers have developed a biocompatible, silver-releasing scaffold that inhibits infection from methicillin-resistant Staphylococcus aureus, or MRSA, in bone. The team’s work was published in Tissue Engineering. The antimicrobial properties of silver ions and the biodegradable scaffold seeded with bone-forming stem cells could be used to coat implants and prevent bone infection, the team suggested in the study. […]