Intersect ENT (NSDQ:XENT) shares jumped yesterday 11% to reach a peak of $13.20 apiece after the company released its preliminary financial results for the 4th quarter, narrowly beating analysts’ expectations on Wall Street. The Menlo Park, Calif.-based company said it expects a total revenue of $24.o – $24.2 million for Q4, slightly ahead of the […]
Study shows Alzheimer’s drug activates stem cells in teeth
Researchers from King’s College London have shown that an Alzheimer’s drug can stimulate the stem cells found in tooth pulp and generate a protective material, dentine, in large cavities. The team’s work was published yesterday in Scientific Reports. If the soft pulp of a tooth becomes infected after a traumatic event, a thin layer of dentine is […]
Intarcia, Calibr collaborate to develop peptide therapeutic for Medici pump
Intarcia Therapeutics and the California Institute for Biomedical Research said today that the 2 groups will collaborate to develop a peptide therapeutic for patients with type II diabetes and obesity. The drug will be derived from Calibr’s stapled-peptide technology platform, combined with Intarcia’s late stage investigational GLP-1 therapy and delivered using the match-sized Medici osmotic […]
Frequency Therapeutics names board of directors
Frequency Therapeutics named its board of directors last week, the company’s 1st public move since it was founded in 2015. Marc Cohen of COBRO Ventures was named chairman. Founder and former CEO of Sepracor, Inc., joined the board as well as Marc Kozin, senior advisor and former president of L.E.K. Consulting. Robert Langer, who co-founded […]
Raumedic highlights drug delivery devices at Pharmapack
Raumedic said today that it will present new drug delivery technologies at Pharmapack in Paris on February 1st and 2nd. The devices enhance drug delivery for oral and injection drugs, the company said in a prepared statement. The Mills River, N.C.-based company said it has developed the oral delivery device XStraw with DS Technology to safely […]
Mast Therapeutics, Savara ink merger deal
Mast Therapeutics (NYSE:MSTX) and privately-held Savara Inc. said today that the 2 companies have landed a definitive merger agreement, combining their operations. The newly-formed Austin, Texas-based company is expected to be named Savara Inc., and trade on the NYSE market under a new ticker symbol. The combined company will focus on advancing a pipeline of […]
Merrimack sells liposome injections to Ipsen for $575m
In a deal that could earn the Cambridge, Mass.-based pharmaceutical company over $1.03 billion, Merrimack Pharmaceuticals (NSDQ:MACK) said yesterday that it is selling its liposome injection cancer drugs, Onivyde and generic Doxil, to Ipsen (EPA:IPN). Merrimack is also slashing its employee headcount down to just 80 people, after laying off 22% of its 400 employees […]
Celsion’s ThermoDox activated by ultrasound in pediatric cancer study
Celsion (NSDQ:CLSN) and Children’s National Health System are teaming up to tackle refractory solid tumors in pediatric patients using a heat-activated chemotherapy drug and noninvasive ultrasound. The Phase I clinical trial, which launched last November, is the 1st of its kind in the U.S. Lawrenceville, N.J.-based Celsion’s ThermoDox is a heat-activated liposomal doxorubicin. In combination with MRI, […]
Taris Biomedical closes enrollment in phase Ib trial for drug-device combo
Taris Biomedical said today that it closed initial enrollment in its phase Ib clinical trial following positive results. The study is evaluating the safety and efficacy of its drug-device combination product that releases gemcitabine continuously into the bladder for 7 days in patients with muscle invasive bladder cancer. Although the study was slated to enroll […]
Neurelis closes Series B for intranasal diazepam spray
Neurelis, Inc. said today that it closed a Series B financing round, led by HBM Healthcare Investments. Other investors included LYZZ Capital, which previously led a Series A funding round for the company. Neurelis will use the funds to complete clinical trials for its intranasal diazepam spray and prepare a new drug application to submit […]