Cancer immunotherapy, a treatment approach that has gained momentum over the past few years, only helps a small fraction of patients. But researchers from the Johns Hopkins University School of Medicine have developed a nanoparticle that may one day help expand the patient population that benefits from immunotherapy. Immunotherapy usually falls into 1 of 2 […]
Nanoparticles
Magnets, nanoparticles open and close blood vessels for targeted drug delivery
Tightly-packed endothelial cells line blood vessels and maintain a highly structured barrier. But researchers from Rice University, Emory University and the Georgia Institute of Technology have found a way to selectively create “leaky” blood vessels for targeted drug delivery. The team’s study, which was published in Nature Communications, reported that magnets can help lead iron-oxide nanoparticles […]
Novavax touts nanoparticle RSV vaccine in women of child-bearing age
Novavax Inc. (NSDQ:NVAX) touted data today from the second Phase II trial of its RSV F nanoparticle vaccine candidate in women of child-bearing age. The research was published in the journal Vaccine. Novavax’s nanomedicine vaccine is being developed to protect infants from the respiratory syncytial virus. The Gaithersburg, Md.-based company presented top-line data from the Phase […]
Nanoparticles: An industry buzzword meets reality
Young startups backed by nanoparticle tech face a world hurdles before reaching the clinic. It’s been decades since the first innovations with nanotechnology – and experts are asking, “Where are all the drugs?” It’s been more than 20 years since the FDA approved the first nanoparticle drug, Doxil. At the time, nanoparticles were heralded as a […]
Revive Therapeutics, University of Wisconsin-Madison ink deal for cannabinoid drug delivery tech
Revive Therapeutics (OTC:RVVTF) said today that it inked a research agreement with the University of Wisconsin-Madison to develop a drug delivery technology for cannibinoids. The research program, led by Jess Reed, is slated to evaluate chitosan-tannin composite biomaterial as a delivery mechanism for cannabinoids. Therapeutic biomaterials made from a composite of chitosan and tannin include […]
Nano-drug hitchhikes on white blood cells directly to tumor site
Researchers from Washington State University have developed a way to target drug delivery to a tumor by attaching the therapeutic to white blood cells. The discovery, which the team describes as a 1st of its kind, could help doctors provide more targeted cancer treatment. The researchers attached a nanoscale particle to a white blood cell […]
Researchers use shock waves, nanoparticles to deliver chemo drugs
Researchers from the University of Turin demonstrated that combining shock waves with nanoparticles can help deliver chemotherapy to tumors in animal models. The team’s work was published in the journal, Endocrine-Related Cancer. Researchers designed the treatment to use extracorporeal shock waves and nanobubbles to more effectively target the cancer drugs to the tumor site. The team […]
Study: Nanoparticle shrinks tumor size by 80% in mouse model
Researchers from the Mayo Clinic have developed a type of cancer-fighting nanoparticle that is designed to shrink breast cancer tumors and prevent recurrence. In a mouse model, the therapy yielded a 70-80% reduction in tumor size and mice treated with the nanoparticles demonstrated resistance to future tumor recurrence a month later. The nanoparticle is coated […]
Kala touts Phase III data for nanoparticle ophthalmic suspension
Kala Pharmaceuticals touted data today from a Phase III trial of its nanoparticle formulation of loteprednol etabonate as a treatment for inflammation and pain in cataract surgery patients. The KPI-121 1% suspension met both primary efficacy endpoints and secondary endpoints and was well tolerated by the trial’s participants. The Waltham, Mass.-based company’s KPI-121 uses Kala’s mucus-penetrating […]
Nanoparticle vaccine triggers immune system to fight multiple cancer types
Researchers from the University of Texas Southwestern Medical Center have developed a nanoparticle vaccine immunotherapy that fights multiple cancer types, according to a preclinical study published in Nature Nanotechnology. The nanovaccine, which the team calls a 1st of its kind, is made up of tumor antigens inside of a synthetic polymer nanoparticle. “What is unique about […]
