Steba Biotech announced today that it received FDA orphan drug designation (ODD) for its Padeliporfin ImPACT for treating UTUC. Padeliporfin ImPACT (immune photo-activated cancer therapy) is designed to offer surgery-like efficacy combined with organ preservation through the intravenous delivery of an inactive drug, according to a news release. Once activated, the drug rapidly triggers the […]
Oncology
TerSera touts study results of infusion reaction prevention treatment
TerSera Therapeutics today announced the presentation of positive data from its study of preventing hypersensitivity infusion reactions. Deerfield, Ill.-based TerSera’s intravenous (IV) cetirizine injection was pitted against IV diphenhydramine in preventing hypersensitivity infusion reactions in patients with breast cancer and other malignancies, according to a news release. The randomized, double-blind Phase 2 study evaluated TerSera’s […]
Amgen to acquire Five Prime Therapeutics for $1.9B
Amgen (NSDQ:AMGN) announced today that it is set to acquire Five Prime Therapeutics (NSDQ:FPRX) for approximately $1.9 billion. Thousand Oaks, Calif.-based Amgen will acquire South San Francisco-based Five Prime for $38 per share in cash, reaching the equity value of approximately $1.9 billion, according to a news release. Amgen is set to add Five Prime’s pipeline […]
VC-backed startup Bionaut Labs intends to use tiny robots for drug delivery
Every once in a while, researchers invoke the 1966 film Fantastic Voyage to describe efforts to use nanotechnology to deliver drugs in the body. A submarine crew shrunk to microscopic size work to damage an injured scientist’s brain in the film. Now, the company Bionaut Labs (Los Angeles) has emerged from stealth mode to describe […]
Janux Therapeutics raises $56M Series A for T cell engager tech
Janux Therapuetics announced today that it closed a $56 million Series A financing as it develops its T cell engager technology. Avalon Ventures led the financing round, while new investors OrbiMed and RA Capital Management joined in. Additionally, existing investors Bregua and Correlation Ventures participated. OrbiMed partner Dr. Peter Thompson and RA Capital Management partner […]
Q BioMed wins federal contract for bone cancer drug
Q BioMed (OTCQB:QBIO) announced today that it signed an agreement for its Strontium89 drug to be included on the Federal Supply Schedule (FSS). New York-based Q BioMed’s agreement with the U.S. government provides U.S. veterans and other federal government agencies and eligible patients access to Strontium89, a treatment for metastatic bone pain related to common […]
FDA approves Oncopeptides treatment for multiple myeloma
Oncopeptides (STO:ONCO) announced today that it received FDA approval for its Pepaxto treatment for multiple myeloma. Waltham, Mass.-based Oncopeptides’ Pepaxto (melphalan flufenamide) received approval in combination with dexamethasone for treating adult patients with relapsed or refractory multiple myeloma who have received at least four prior lines of therapy and whose disease is refractory to at […]
BriaCell Therapeutics closes $25M offering
BriaCell Therapeutics (NSDQ:BCTX) announced today that it closed an underwritten public offering worth $25 million. Berkeley, Calif.-based BriaCell offered more than 4.85 million common units comprised of one share of common stock and one warrant to purchase one share of common stock priced at $4.25 per unit, according to a news release. Additionally, the offering […]
ForDoz enters manufacturing agreement with LipoMedix
ForDoz Pharma announced today that it entered into an agreement with LipoMedix to manufacture its lead compound for a clinical trial. LipoMedix’s pegylated liposomal Promitil (PL-MLP) is designed for the selective delivery of the therapeutic agent to cancer-affected tissues and is suited for cancer chemoradiotherapy, according to a news release. Studies have shown PL-MLP to […]
OncoSec announces positive results in metastatic melanoma case study
The International Journal of Surgery Case Reports has published a case study on the use of the humanized antibody Keytruda (pembrolizumab) and tavokinogene telseplasmid (TAVO) from OncoSec (NSDQ:ONCS) for treating metastatic melanoma. The study involved a patient with stage IIB, pT3b melanoma who initially underwent tumor resection but experienced regional recurrence and later disease progression […]