• Skip to primary navigation
  • Skip to main content
  • Skip to primary sidebar
  • Skip to footer
  • Advertise
  • Subscribe

Drug Delivery Business

  • Clinical Trials
  • Research & Development
  • Drug-Device Combinations
  • FDA
  • Pharmaceuticals
  • Policy

Diasome lands $30m to fund clinical trials of liver-targeted insulin

July 5, 2017 By Sarah Faulkner

Diasome Pharmaceuticals said today that it inked a funding deal that could bring the company up to $30 million. The round was led by Medicxi and contributed to by JDRF T1D Fund, Black Beret Life Sciences and McDonald Partners.

The Cleveland-based company said it plans to use the funds to support the clinical development of its hepatocyte directed vesicles (HDV) technology. Diasome’s additive is designed to direct the delivery of commercial insulin therapies to the liver’s hepatocytes.

The company is conducting a Phase IIb study of HDV-insulin in subjects with Type I diabetes and Diasome said it is almost at the end of its enrollment period. The company also launched two new Phase II studies of its technology in patients with Type I diabetes within the last month.

“The investment by Medicxi, JDRF T1D Fund, Black Beret, and McDonald Partners represents a significant validation of Diasome’s technology, and we will benefit from their track records of working with and advising successful drug development companies” CEO Robert Geho said in prepared remarks.

“It has never been understood why insulin as a hormone replacement therapy cannot mimic the endogenous insulin activity. With HDV liver-targeted insulin, Diasome is providing a simple and elegant answer to this problem, with their preliminary human data showing that HDV makes commercial insulin more physiological, and therefore, significantly more effective. We look forward to assessing the results of the ongoing Phase II studies,” Medicxi founding partner Michele Ollier said.

“Diasome is the first investment from Medicxi’s Growth Fund I, and the company represents a unique and disruptive opportunity in the global diabetes field,” Medicxi founding partner Giuseppe Zocco added. “The HDV system’s proprietary mechanism of action and physiology-based design are without precedent in the diabetes pharmaceutical landscape.”

Along with the investment, Ollier and Zocco joined Diasome’s board of directors.

“JDRF knows how challenging it has been to provide patients with Type 1 diabetes insulin therapies that are able to lower overall blood glucose levels while avoiding and protecting against low blood sugar, or hypoglycemic, episodes,” Jonathan Behr, managing director of the JDRF T1D fund, said. “We recognize that HDV + insulin therapy could be a significant advance for patients, and we are excited to support Diasome’s team as they move forward.”

Want to stay on top of DDBN content? Sign up for our e-mail newsletter for a weekly dose of drug-device news.

Filed Under: Clinical Trials, Diabetes, Featured, Funding Roundup, Pharmaceuticals Tagged With: diasomepharmaceuticals

IN CASE YOU MISSED IT

  • Insulet hires new chief HR officer from J&J
  • Breakthrough T1D, Mattel debut Barbie doll with type 1 diabetes
  • Medtronic Diabetes names CFO with consumer experience ahead of separation
  • Diabeloop launches insulin delivery algorithm in Germany
  • GlucoModicum has positive data for needle-free CGM

Primary Sidebar

“ddb
EXPAND YOUR KNOWLEDGE AND STAY CONNECTED
Get the latest news and trends happening now in drug delivery.

MEDTECH 100 INDEX

Medtech 100 logo
Market Summary > Current Price
The MedTech 100 is a financial index calculated using the BIG100 companies covered in Medical Design and Outsourcing.

Footer

Drug Delivery Business News Logo

MassDevice Medical NETWORK

MassDevice
DeviceTalks
Medical Tubing + Extrusion
Medical Design & Outsourcing
MedTech100 Index
Drug Discovery & Development
Pharmaceutical Processing World
Medical Design Sourcing
R&D World

DRUG DELIVERY BUSINESS NEWS

Subscribe to Drug Delivery’s E-Newsletter
Advertise with us
About
Contact us
Privacy
Listen to our Weekly Podcasts

Copyright © 2025 · WTWH Media LLC and its licensors. All rights reserved.
The material on this site may not be reproduced, distributed, transmitted, cached or otherwise used, except with the prior written permission of WTWH Media.

Privacy Policy | RSS