Inovio Pharmaceuticals (NSDQ:INO) reported today that its synthetic HIV vaccine, Pennvax-GP, demonstrated durable antibody and T cell immune responses throughout a Phase I trial. The company found that Pennvax-GP plasmids delivered intradermally with Inovio’s Cellectra device triggered equivalent or superior immune responses in healthy volunteers compared to intramuscular delivery of the plasmids using the same device. […]
Delcath registers $100m offering
Delcath Systems (NSDQ:DCTH) registered a $100 million offering with the SEC this week to support the development of its system designed to administer high-dose chemotherapy to the liver. The company’s product, melphalan hydrochloride for injection for use with the Delcath hepatic delivery system, won CE Mark clearance in Europe in 2012 and is under consideration by […]
Researchers develop nanodevice to deliver immunotherapy
Researchers at Houston Methodist Research Institute have created a nanodevice that can be used to deliver immunotherapy to treat triple-negative breast cancer. The tiny device is designed to be inserted directly into a tumor, delivering a localized, sustained-release dose of therapy and eliminating the need for patients to undergo IV treatments. The scientists described their […]
Boston Scientific CEO talks pricing pressure for drug-eluting stents
On an earnings call with analysts this week, Boston Scientific (NYSE:BSX) CEO Mike Mahoney touted the momentum of his company’s drug-eluting stent portfolio but noted that the technologies continue to face headwinds in the U.S. thanks to pricing pressure. The Mass.-based company reported third-quarter profits of $432 million, or 31¢ per share, on sales of $2.39 […]
Oyster Point Pharma touts trial results for intranasal dry eye disease drugs
Oyster Point Pharma touted data today from two Phase IIb trials assessing its nasal spray products for the treatment of dry eye disease. Both studies showed that use of OC-01 and OC-02 led to improvements in multiple measures of eye dryness symptoms, according to the Princeton, N.J.-based company. Oyster Point’s Onset study evaluated the safety […]
ICU Medical warns about leaks in Thermoset drug-delivery systems
ICU Medical (NSDQ:ICUI) issued a warning this month that it received reports of leakage with some lots of its Thermoset drug-delivery systems in Europe, the Middle East and Africa. The company noted that the affected Thermoset products included its room-temperature closed-loop drug-delivery system with an in-line temperature probe, as well as its Iced Thermoset system designed […]
FDA to review Xeris’ glucagon rescue pen auto-injector
Xeris Pharmaceuticals (NSDQ:XERS) said today that the FDA accepted its new drug application for a ready-to-use liquid glucagon rescue pen device. The company’s product is designed to treat severe hypoglycemia in people with diabetes. The FDA is slated to make a decision about Xeris’ pen by June 10, 2019. “The FDA acceptance of our NDA for […]
Purdue acquires non-opioid painkiller with SpineThera purchase
Purdue Pharma announced today that it acquired SpineThera and a dexamethasone epidural product designed to treat low back pain. SpineThera’s SX600 therapy features tiny, biodegradable microspheres which enable sustained-release of dexamethasone. “We are pleased to partner with SpineThera to support further development of its novel steroid product for epidural injection for patients who suffer from […]
Novo Nordisk partners with Flex for digital diabetes management tools
Flex (NSDQ:FLEX) today announced a partnership with Novo Nordisk (NYSE:NVO) to develop digital diabetes management tools using Flex’s BrightInsight IoT platform. Novo Nordisk plans to use Flex’s BrightInsight system to build and manage connected medical devices and the corresponding data. The company’s IoT platform is designed to enable organizations to develop digital health devices while remaining […]
KemPharm inks drug discovery deal with AI-driven biopharma
KemPharm (NSDQ:KMPH) said today that it inked a collaboration with twoXar to develop prodrug-based therapies for an array of therapeutic indications. According to the deal, twoXar’s artificial intelligence-based drug discovery technology will be used alongside KemPharm’s Ligand Activated Therapy platform to identify and develop new prodrug therapies. In conjunction with its deal with twoXar, KemPharm also inked a research and […]
