Clearside Biomedical (NSDQ:CLSD) said today it will redirect its R&D efforts from its pre-clinical axitinib wet age-related macular degeneration therapy to its Zuprata diabetic macular edema treatment. The Alpharetta, Ga.-based company said that recent trial results from other companies investigating combination therapies for wet AMD have led Clearside to reconsider its proprietary suspension formulation of […]
Research & Development
Study: Nanotechnology could cut dose of HIV treatment in half
Researchers from the University of Liverpool presented data this week evaluating the use of nanotechnology to improve drug therapies for HIV patients. The team touted its data at the Conference on Retroviruses and Opportunistic Infections in Seattle. The trial enrolled healthy patients and evaluated the use of orally-dosed solid drug nanoparticles to optimize HIV therapy, according […]
Study: Industry funding biases drug trials in favor of sponsors
Researchers from the University of Sydney published a review this week, concluding that industry-funded drug trials are often biased in favor of the sponsors’ products. According to Lisa Bero of the university’s Charles Perkins Centre, the study provides “definitive evidence that pharmaceutical industry funding of drug studies biases the results and conclusions to look favourable […]
Researchers develop smart drugs using ‘DNA computers’ for controlled delivery
Researchers from the Eindhoven University of Technology have developed the 1st “DNA computer” that can detect several antibodies in the blood and perform calculations based on what it detects. The team published their work in Nature Communications and said that it’s an important step towards developing smart drugs that allow for more targeted and controlled medication delivery. […]
How virtual and mixed reality are changing drug delivery and device design
Kai Worrell believes that virtual and mixed reality may change the way companies design medical devices, and he’s putting that idea into practice. “We think it’s going to transform the way we do feasibility testing and cognitive walk-through simulations,” he said. “We think it’s going to help us understand the cognition of our users, clinical […]
Insulet touts Omnipod Horizon hybrid closed-loop system in patients with T1D
Insulet (NSDQ:PODD) touted data today from the 1st feasibility study of its Omnipod Horizon hybrid closed-loop system in patients with Type 1 diabetes. Data from the study showed that the Omnipod automated glucose control algorithm performed well, with minimal hypoglycemia, and that it was safe. The Billerica, Mass.-based company enrolled 24 patients with Type 1 diabetes […]
Virus shells target and deliver drugs to cancer cells
Researchers from Australia and the UK have developed virus-like nanoparticles to target and deliver drugs to cancer cells. The team’s work, which was published in the journal ACS Nano, showed that the particle could be produced in plants and that it can shuttle small molecules to cancer cells for targeted treatment. The team, lead by Frank […]
ICU Medical touts dosing errors study
ICU Medical (NSDQ:ICUI) said today that a multi-hospital study showed improvements in potentially catastrophic dosing errors and drug library compliance when its Plum infusion pumps and Hospira (NYSE:HSP) MedNet safety software were integrated with the hospitals’ electronic medical records. The rate of potentially catastrophic dosing errors fell by 52% after smart-pump EMR integration, the study found, […]
Abbott touts association between monitoring and improved glucose control
Abbott (NYSE:ABT) touted results today from real-world use data for its FreeStyle Libre blood glucose monitoring system. The data showed that people using its FreeStyle Libre system to monitor their glucose levels spend less time in hypoglycemia or hyperglycemia and have improved average glucose levels. More than 50,000 diabetes patients using the FreeStyle Libre system checked […]
Tiny magnetic implant delivers drug locally
Researchers from the University of British Columbia have developed a magnetic drug implant that measures just 6 millimeters in diameter and can deliver a drug locally to a targeted tissue. The team’s work was published in the journal Advanced Functional Materials. The device is a silicone sponge with magnetic carbonyl iron particles, wrapped in a round […]
