Purdue researchers tout nasal tuberculosis vaccine development strategy

August 20, 2021 By Sean Whooley

Purdue tuberculosis vaccine-mittalLO — Dr. Mittal conducts research on the potential tuberculosis vaccine. [Image from Suresh Mittal/Purdue University]

Researchers at Purdue University and Houston Methodist Research Institute are touting a novel strategy for developing a tuberculosis (TB) vaccine.

Bacillus Calmette-Guérin (BCG) is widely used as a vaccine against TB, but the researchers say it has a variable protection against neonatal and adult pulmonary TB, with protection ranging from 0% to 80% among infants. Despite routine vaccinations for children, mycobacterium tuberculosis (Mtb) continues to disseminate into brain and tuberculosis meningitis.

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