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Researchers use skull-implantable ultrasound to help deliver chemotherapy to the brain

May 5, 2023 By Sean Whooley

Northwestern Medicine skull-implantable ultrasound for chemotherapy delivery
[Screenshot from video provided by Northwestern Medicine]
Northwestern Medicine shared results from a first-in-human clinical trial for a skull-implantable ultrasound device that supports chemotherapy delivery.

The device opened the blood-brain barrier to repeatedly permeate large, critical regions of the human brain. This enabled the delivery of chemotherapy injected intravenously.

With the patient awake, a four-minute procedure opens the blood-brain barrier and patients go home after a few hours. Results from the Northwestern study demonstrated both a safe and well-tolerated treatment. Some patients even reached up to six cycles of chemotherapy treatment.

The paper published on May 2 in The Lancet Oncology.

Get the full story at our sister site, Medical Design & Outsourcing.

Filed Under: Clinical Trials, Drug-Device Combinations, Neurological, Oncology Tagged With: chemotherapy, Northwestern University, ultrasound

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About Sean Whooley

Sean Whooley is an associate editor who mainly produces work for MassDevice, Medical Design & Outsourcing and Drug Delivery Business News. He received a bachelor's degree in multiplatform journalism from the University of Maryland, College Park. You can connect with him on LinkedIn or email him at swhooley@wtwhmedia.com.

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