Researchers at Washington University have developed nanoparticles to treat the inflammation that wears away at joint cartilage in patients with osteoarthritis. Traditional treatment methods to reduce inflammation involve steroid injections, but the body quickly washes them away, leaving the cells vulnerable to more inflammation. “I see a lot of patients with osteoarthritis, and there’s really […]
Nanoparticles
‘Connectosomes’ efficiently deliver chemo to targeted cells
Researchers have developed a new form of nanoparticles called “connectosomes” that can efficiently deliver chemotherapy to human cells more efficiently than traditional delivery methods, according to a report out of the University of Texas at Austin. The team, who published their research in the Journal of the American Chemical Society, equipped the connectosomes with gap junctions […]
Hospital researchers explore MRI for drug delivery
Researchers have programmed an MRI scanner to simultaneously monitor magnetized particles while propelling them through blood vessels as a means to locally deliver drugs. Existing approaches combine the magnetic force from an MRI scanner with the force produced by particle collisions. But traditionally, it’s challenging to image using the MRI scanner and propel the particles […]
Dicerna bails on EnCore lipid nanoparticle tumor delivery program
Dicerna Pharmaceuticals (NSDQ:DRNA) said yesterday that it plans to spike the development program for its lipid nanoparticle delivery system for solid tumors because its preliminary results don’t meet expectations. The Cambridge, Mass.-based company evaluated its lipid nanoparticle, DCR-MYC, in a pair of clinical trials – a Phase I study of patients with solid tumors, hematological […]
