Boston Children’s Hospital announced today that it partnered with ElevateBio for a five-year cell and gene therapy advancement program. The collaborative agreement will seek to advance cell and gene therapy programs originating out of Boston Children’s Hospital with an introduction to Boston Children’s translational research capabilities. Cambridge, Ma.-based ElevateBio will offer Boston Children’s researchers access […]
Boston Children's Hospital
Medtronic responds to usability concerns for its MiniMed 670G insulin pump
Medtronic (NYSE:MDT) responded to a study presented this week which highlighted usability concerns with its MiniMed 670G automated insulin pump, writing that the company had “made many enhancements to the system since the study was done which would likely mitigate many of the issues experienced.” Earlier this week, physicians from Boston Children’s Hospital reported that nearly […]
Study examines usability of hybrid closed-loop insulin pump
Data from an 83-person study of Medtronic‘s (NYSE:MDT) MiniMed 670G hybrid closed-loop insulin pump showed that nearly one-fifth of participants stopped using the device after struggling with the technical demands of the system, researchers reported. Medtronic’s MiniMed 670G device is designed to automatically track and adjust a patient’s blood sugar levels by measuring blood glucose […]
Researchers question use of antibiotic shunts in hydrocephalus patients
Led by neurosurgeon Dr. Benjamin Warf, a team of researchers from Boston Children’s Hospital published a study this month questioning the benefits of using shunts impregnated with antibiotics to treat hydrocephalus. Hydrocephalus, which affects roughly 400,000 children each year, is characterized by fluid accumulation in the brain. Surgeons use shunts to drain the patient’s excess […]
Researchers reverse diabetes in mice by infusing them with blood stem cells
Researchers at Boston Children’s Hospital successfully reversed Type I diabetes in a mouse model using blood stem cells, according to a study published this week in Science Translational Medicine. The researchers used cells that were pre-treated to make more of a protein, PD-L1, which is deficient in mice and people with Type I diabetes. “There’s really […]
How slugs, snails & worms inspired Gecko Biomedical’s biocompatible sealant
The story behind Gecko Biomedical’s biocompatible sealant starts in the summer of 2009, when Boston Children’s Hospital‘s chief of cardiac surgery reached out to Jeffrey Karp about a problem he was experiencing in the operating room. Dr. Pedro del Nido told Karp, a professor of medicine at Harvard and the director of the Laboratory for […]
Amgen, Boston Children’s Hospital partner to find genes linked to pain disorders
Amgen (NSDQ:AMGN) announced today that it inked a one-year collaboration with Boston Children’s Hospital to study patients with pain syndromes in an effort to identify potential genetic targets. The collaboration will combine Amgen’s work in genetic target identification and the division of pain medicine at Boston Children’s Hospital. “Traditional approaches to analgesic drug discovery have been […]
Liposomes triggered by ultrasound enable targeted pain-relief
Researchers at Boston Children’s Hospital have developed a technology to non-invasively trigger the release of nerve-blocking agents, helping to provide targeted pain-relief to patients as an alternative to addictive opioids. The team’s work was published yesterday in Nature Biomedical Engineering. “Opioid abuse is a growing problem in healthcare,” senior author Dr. Daniel Kohane said in prepared […]
Researchers tout preclinical results for one-shot vaccination method
Researchers from Boston Children’s Hospital said today that they achieved strong vaccine responses in preclinical models by adding adjuvants to boost the immune response. The team’s work was published the Journal of Clinical Investigation-Insight and the Journal of Allergy and Clinical Immunology. Vaccines have the potential to drastically reduce infant mortality, the researchers said, but newborns often don’t […]
Fibrosis: How to prevent it in medical device implants
Massachusetts Institute of Technology (MIT) and Boston Children’s Hospital researchers have discovered a way to prevent fibrosis from forming around medical device implants by blocking certain cells. The body’s immune system usually attacks implanted medical devices that are used for drug delivery, sensing or tissue regeneration. Defense cells in the body try to isolate the […]