Researchers from the University of Tokyo treated the surfaces of nanoparticles with polymers and enabled the transport of quantum dots into cells, according to a study published in Science and Technology of Advanced Materials. By coating nanoparticles with MPC polymers, researchers can make substances that are easily transported and delivered into the blood or other tissue because […]
Nanoparticles
NanoViricides inks deal for shingles study
NanoViricides, Inc. (NYSE:NNVC) said today that it inked a deal with SUNY Upstate Medical University for the evaluation of its nanovirivides drug candidates against varicella zoster virus, also called the shingles virus. The goal of these in vitro, ex vivo, and in vivo studies will be to help select a clinical drug development candidate for toxicology and safety evaluation […]
Cerulean promotes Eliasof to senior VP & CSO | Personnel Moves, Oct. 26, 2016
Cerulean promotes Eliasof to senior VP & CSO Cerulean Pharma (NSDQ:CERU) said today that it named Scott Eliasof as senior VP and CSO, promoting him from VP of research. He joined the Waltham, Mass.-based company in 2007. Before coming on board to Cerulean, Eliasof was the director of the chemical biology platform at the Broad […]
Jivana Biotechnology raises $1m for targeted cancer therapy
Jivana Biotechnology raised $1 million for its preclinical work using targeted RNA-based therapies to treat a variety of cancers, according to a regulatory filing the Oak Park, Ill.-based company submitted this week. The minimum investment from an outside investor was $50,000, the company reported, and it used an estimated $125,000 for payments to its executive […]
Bacterial nanostructures developed to locally deliver proteins
Spanish researchers demonstrated that bacterial inclusion bodies, non-toxic nanostructures, hold promise for a sustained, local delivery of protein drugs by mimicking components of a mammal’s endocrine system. New materials developed as controllable, localized systems of drug delivery often aim to be immobilized in a given tissue as a drug “depot” for long term supply of […]
Solid drug nanoparticles could improve delivery of HIV therapies
Researchers from the University of Liverpool have developed a method of delivering pediatric HIV drugs using solid drug nanoparticles, according to a study published today in Nature Communications. There are no clinically available oral nanotherapies for HIV patients and pediatric HIV medicines are not widely available, according to the researchers. The team examined a current pediatric […]
Gold nanoparticles hold promise for pancreatic cancer treatment
Gold nanoparticles could be an important part of developing a treatment for pancreatic cancer, according to new research published yesterday in the journal ACS Nano. Previous work demonstrated that gold nanoparticles can be an effective vehicle to carry chemotherapy drugs into tumors. They can also act as a target to enhance the impact of radiation on […]
Cerulean, Novartis ink $5m deal to co-develop nanoparticle-drug conjugates
UPDATED Oct. 20, 2016, with Cerulean share price movement. Cerulean Pharma Inc. (NSDQ:CERU) said today that it inked a deal with Novartis (NYSE:NVS) to develop nanoparticle-drug conjugates. The products will match Cerulean’s tumor-targeting tech with Novartis compounds directed at up to 5 targets. The agreement calls for Cerulean to receive $5 million plus funding for 5 full-time equivalents […]
Keystone Nano wins orphan designation for ceramide liver cancer treatment
Keystone Nano said today that its ceramide nanoliposome won orphan drug status from the FDA for the treatment of liver cancer. The designation provides the company with a window of market exclusivity after product approval. The State College, Penn.-based company touted its nanoliposome delivery system as being able to load both water-loving and water-hating compounds and […]
Report finds ethosomes as promising transdermal delivery mechanism
Ethosomes – nanocarriers loaded with ethanol – can penetrate the skin’s protective layers and deliver a variety of drugs, a review published in Current Clinical Pharmacology reported today. Transdermal delivery of drugs is touted by some researchers as promising, since it’s noninvasive and avoids any interaction with the gastrointestinal tract. Ethosomes are malleable and their […]
