Mylan (NSDQ:MYL) last week agreed to pay $465 million to settle claims that it underpaid Medicaid for its EpiPen auto-injector by misclassifying the device as a generic. Last week, the Centers for Medicare & Medicaid Services said it spent $797 million on the emergency allergy treatment between 2011 and 2015, including rebates. The Canonsburg, Pa.-based company has […]
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Lupin, MonoSol Rx ink licensing deal for pediatric products
Lupin Pharmaceutical (NSE:LUPIN) said last week that it inked a licensing agreement with MonoSol Rx to develop pediatric products using MonoSol’s drug-delivery technology. Warren, N.J.-based MonoSol touts its dissolvable film, PharmaFilm, as a quick-dissolving system that’s easy to administer and masked by taste. The sublingual film is designed to support pediatric populations that often have trouble swallowing […]
Report finds ethosomes as promising transdermal delivery mechanism
Ethosomes – nanocarriers loaded with ethanol – can penetrate the skin’s protective layers and deliver a variety of drugs, a review published in Current Clinical Pharmacology reported today. Transdermal delivery of drugs is touted by some researchers as promising, since it’s noninvasive and avoids any interaction with the gastrointestinal tract. Ethosomes are malleable and their […]
CMS finds Mylan overcharged Medicaid for EpiPens for years
The Centers for Medicare & Medicaid Services said this week that Mylan Pharmaceuticals (NSDQ:MYL) has been overcharging Medicaid for its EpiPen auto-injector for years, despite being warned that it should have paid bigger rebates. CMS said that between 2011 and 2015, Medicaid spent $797 million on the epinephrine auto-injector after deducting rebates, marking the 1st […]
‘Connectosomes’ efficiently deliver chemo to targeted cells
Researchers have developed a new form of nanoparticles called “connectosomes” that can efficiently deliver chemotherapy to human cells more efficiently than traditional delivery methods, according to a report out of the University of Texas at Austin. The team, who published their research in the Journal of the American Chemical Society, equipped the connectosomes with gap junctions […]
Report: Drug device market to reach $1.8B by 2024
The global drug device combination market is expected to reach $17.7 billion by 2024, according to a new report from Grand View Research. The report points to minimally invasive alternatives like transdermal patches as high-impact growth drivers in the industry. As researchers develop these products, regulatory agencies have taken notice and the report notes that […]
Motion-directed microrobots for targeted drug delivery
Researchers have created tiny ‘microbots’ that are able to move and react in a fashion similar to bacteria, according to a report from the Max Planck Institute for Intelligent Systems. Bacteria use flagella to move, directed by stimuli like sources of light or the earth’s magnetic field. Researchers have developed synthetic microrobots with motility and phototaxis, […]
Enable Injections lands $30m Series A for large-volume injector
Enable Injections Inc. said today that it closed a $30 million Series A round to bring its large-volume injector to market. The Cincinnati, Ohio-based company’s Enable Injector adheres to a patient’s body and delivers biologic doses as large as 50 milliliters. It can be used at work or at home, providing an alternative to costly […]
Nobel chemistry prize goes to molecular machinery
A group of European scientists won the 2016 Nobel Prize for chemistry for developing the “world’s smallest machines,” which could be used to revolutionize drug delivery. Jean-Pierre Sauvage, J. Fraser Stoddart and Bernard Feringer claimed the $931,000 prize (8 million Swedish crowns) for work that Feringer described as having “endless” potential, according to Reuters. “Think of a […]
QuiO raises $1m for smart injection device
QuiO said last week that it closed a $1.05 million seed round led by undisclosed investors to finish developing its smart injection device, prep for pilot studies and an FDA 510(k) submission. The New York-based company is developing a smart injection device and software to monitor patient adherence to clinical trial and daily regimens. Average […]