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Preclinical Trials

Vaxxas licenses COVID-19 vaccine for patch delivery system, expects to finish Phase 1 trial this year

March 23, 2022 By Sean Whooley

Vaxxas micropatch vaccine COVID-19

Vaxxas announced today that it was granted an exclusive license for a next-generation COVID-19 vaccine to be used with its delivery patch. Cambridge, Massachusetts-based Vaxxas received the license from The University of Texas at Austin for its HexaPro SARS-CoV-2 spike subunit vaccine. The license comes with a companion background technology license from the U.S. National […]

Filed Under: Business/Financial News, Clinical Trials, Drug-Device Combinations, Featured, Pharmaceuticals, Preclinical Trials Tagged With: coronavirus, COVID-19, University of Texas at Austin, Vaxxas

Virpax completes FDA-required preclinical studies for pain-treating topical spray

March 22, 2022 By Sean Whooley

Virpax

Virpax Pharmaceuticals (Nasdaq:VRPX) announced today that it completed all FDA-required preclinical studies for its Epoladerm product. Berwyn, Pennsylvania-based Virpax designed its Epoladerm investigational pre-filled topical spray analgesic product for the non-addictive management of chronic pain associated with osteoarthritis (OA) of the knee. Its completed investigational new drug application (IND)-enabling studies included dermal toxicity, sensitization, irritation, […]

Filed Under: Clinical Trials, Drug-Device Combinations, Featured, Food & Drug Administration (FDA), Pain Management, Pharmaceuticals, Preclinical Trials, Research & Development Tagged With: FDA, Virpax Pharmaceuticals

MIT researchers study the best size for nanoparticles to stop internal bleeding

February 17, 2022 By Sean Whooley

MIT Nanoparticles Internal traumatic injury

MIT researchers are examining how different-sized polymer nanoparticles circulate in the body, with a goal of treating traumatic injuries. Researchers are developing injectable nanoparticles that can attract cells to help stop the bleeding at the site of an internal injury until a patient can get to a hospital for treatment. To highlight the mechanism of […]

Filed Under: Clinical Trials, Drug-Device Combinations, Featured, Nanoparticles, Preclinical Trials Tagged With: Massachusetts Institute of Technology, mit

Virpax touts study results for intranasal spray for treating acute, chronic pain

February 10, 2022 By Sean Whooley

Virpax

Virpax Pharmaceuticals (NSDQ:VRPX) today announced promising results from preclinical studies for its Envelta intranasal spray. Berwyn, Pennsylvania-based Virpax designed Envelta (NES100), an endogenous enkephalin intranasal spray, for treating acute and chronic pain, including pain associated with cancer. According to a news release, findings from preclinical dose range-finding studies for Envelta complement previous positive preclinical toxicology […]

Filed Under: Clinical Trials, Drug-Device Combinations, Featured, Pain Management, Pharmaceuticals, Preclinical Trials Tagged With: Virpax Pharmaceuticals

Giiant Pharma extends seed round with $1.25M

June 30, 2021 By Sean Whooley

GIIANT Pharma_Logo_RGB_noname

Giiant Pharma announced today that it added $1.25 million to its seed financing round to ensure reaching clinical proof-of-concept for its Precision Delivery technology platform. Montreal-based Giiant’s $750,000 in funding from AQC Capital, plus $500,000 from CQDM, adds to the seed round closed last month to bring the company’s total funding to nearly $15 million. […]

Filed Under: Business/Financial News, Drug-Device Combinations, Featured, Funding Roundup, Pharmaceuticals, Preclinical Trials Tagged With: Giiant Pharma

MedinCell to begin regulatory development of long-acting injectable malaria treatment

June 15, 2021 By Sean Whooley

MedinCell

MedinCell announced that its long-acting injectable malaria treatment is ready to enter into the stages of regulatory development. Montpellier, France–based MedinCell conducted an in vivo proof of concept on cattle that demonstrated three-month mosquitocidal effectiveness in the injectable, long-acting formulation of Ivermectin using the company’s BEPO delivery technology. The company designed the investigational mdc-STM product […]

Filed Under: Clinical Trials, Drug-Device Combinations, Featured, Pharmaceuticals, Preclinical Trials, Research & Development Tagged With: MedinCell

Giiant Pharma raises $11M for drug delivery platform for gastroenterology

May 21, 2021 By Sean Whooley

GIIANT Pharma_Logo_RGB_noname

Giiant Pharma announced today that it closed a $11 million seed financing round for its drug delivery technology platform. Montreal-based Giiant develops the Precision Delivery technology platform, which originated from the work of former Merck Frosst scientists, according to a news release. The company designs gut-restricted, tissue-specific, small-molecule drug therapeutics to be delivered through the […]

Filed Under: Business/Financial News, Drug-Device Combinations, Featured, Funding Roundup, Pharmaceuticals, Preclinical Trials Tagged With: Giiant Pharma

Intravacc touts preclinical, non-human results for COVID-19 nasal spray vaccine

April 7, 2021 By Sean Whooley

Intravacc

Intravacc is today touting positive pre-clinical results of its SARS-CoV-2 nasal spray vaccine candidate in non-human subjects. Bilthoven, Netherlands-based Intravacc’s SARS-CoV-2 outer membrane vesicle (OMV)-based recombinant spike protein (rSp) nasal spray candidate was observed in four groups of mice and four groups of hamsters, all of which received two intranasal immunizations on day one and […]

Filed Under: Drug-Device Combinations, Featured, Pharmaceuticals, Preclinical Trials Tagged With: coronavirus, COVID-19, COVID-19 vaccine, Intravacc

Johns Hopkins researchers tout medicine-delivering microdevices

November 3, 2020 By Sean Whooley

Johns Hopkins researchers are touting microdevices that can latch onto intestinal mucosa and release drugs into the body. Led by engineering professor David Gracias and gastroenterologist Dr. Florin Selaru, the team of researchers and biomedical engineers designed and tested shape-changing microdevices that they say can mimic the way the parasitic hookworm affixes itself to an […]

Filed Under: Clinical Trials, Drug-Device Combinations, Featured, Preclinical Trials, Research & Development Tagged With: Johns Hopkins

OncoSec, Inovio testing COVID-19 vaccines

April 8, 2020 By Sean Whooley

OncoSec Medical (NSDQ:ONCS) and Inovio Pharmaceuticals (NSDQ:INO) announced that they are testing potential COVID-19 vaccines after the latter received investigational new drug clearance from the FDA. Inovio received an IND nod, while OncoSec’s is pending, but both companies are pursuing a first-in-human Phase 1 clinical trial for their vaccines, according to separate news releases. OncoSec is using […]

Filed Under: Business/Financial News, Clinical Trials, Discovery, Featured, Food & Drug Administration (FDA), Immunotherapy, Pharmaceuticals, Preclinical Trials, Regulatory/Compliance, Research & Development, Respiratory Tagged With: coronavirus, COVID-19, Inovio Pharmaceuticals, OncoSec Medical

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