SanBio Inc. (TYO:4592) released 1-year interim data from the phase 1/2a, open-label, single-arm dose escalation study of its intracerebral stem cell implant designed for stroke patients. The Mountain View, Calif.-based company touted the results, which indicated that itsSB623 stem cell treatment was generally safe, well-tolerated and associated with improved motor functions in patients suffering with chronic impairment following […]
Research & Development
Lab models drug-eluting polymer beads in blood flow
Researchers from the University of Huddersfield developed a method to predict how drug-eluting polymer beads can affect the body if they are modified. The UK team of researchers published their work in the European Journal of Pharmaceutical Sciences. Polymer beads are frequently used in cases of liver cancer, where they’re injected into a patient’s arteries to block […]
Encapsulating single cells in tunable hydrogel could boost cell therapies
Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University and the Harvard John A. Paulson School of Engineering and Applied Sciences have developed a microfluidic approach to trap individual cells within a hydrogel material that can be tuned to match the physiological conditions of the body, according to a study published this […]
Droplet ‘taxicabs’ transport nanoparticles into cell
Researchers from the University of Massachusetts-Amherst have developed polymer-stabilized droplet carriers that can identify and engulf nanoparticles to bring them into a cell. The team was inspired by proteins that can recognize microbes or debris and then encapsulate the material to get rid of it. The team believes that this demonstration of surface-to-surface nanoparticle transport, […]
Polymeric nanoparticles transport quantum dots into cells
Researchers from the University of Tokyo treated the surfaces of nanoparticles with polymers and enabled the transport of quantum dots into cells, according to a study published in Science and Technology of Advanced Materials. By coating nanoparticles with MPC polymers, researchers can make substances that are easily transported and delivered into the blood or other tissue because […]
PharmaJet, Vaccibody collaborate on needle-free HPV vaccine
PharmaJet and Vaccibody inked a collaborative deal to provide needle-free injection tech for the development of a human papillomavirus vaccine. HPV is the cause of virtually all cervical cancer, according to the National Cancer Institute, and just 2 types of HPV, 16 and 18, are responsible for about 70% of all cases. PharmaJet’s device is […]
Researchers boost stem cell programming with gene mutation
Researchers discovered a way to increase the efficiency of stem cell programming using research on a rare genetic disease, according to a study published in the Proceedings of the National Academy of Sciences. Induced pluripotent stem cells are created from skin cells and can be transformed into any type of cell in the body. Using existing […]
Dipexium crashes after Locilex Phase III trials fail
Shares in Dipexium Pharmaceutical (NSDQ:DPRX) dived 84% today after it reported that its OneStep-1 and OneStep-2 Phase III clinical trials of Locilex in patients with mild infections of diabetic foot ulcers did not meet its primary or secondary clinical endpoints. Both trials failed to show any meaningful difference in wound closure rate between the Locilex arm and the […]
Imprimis touts ‘dropless therapy’ study for cataract surgery
Imprimis Pharmaceuticals (NSDQ:IMMY) touted data today from a peer-reviewed study of patients who received its “dropless therapy” following cataract surgery. The San Diego-based company uses a compounded antibiotic and steroid formulation in single, injectable doses administered by physicians following ocular surgery. The treatment is designed to eliminate the need for patient-administered eye drops, potentially eliminating patient […]
Cytori touts regenerative cell therapy data
Cytori Therapeutics (NSDQ:CYTX) touted the publication of preclinical safety and efficacy data for its cell therapy treatment for combined radiation and thermal injury. The San Diego-based company said the current healthcare system is ill-prepared to care for large numbers of patients that require simultaneous treatment and that patients with severe burns commonly suffer with prolonged […]
