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Research & Development

Smart patch monitors blood, releases blood thinners to prevent clots

November 29, 2016 By Sarah Faulkner

Researchers from the North Carolina State University and the University of North Carolina at Chapel Hill have developed a patch designed to monitor a patient’s blood and release blood-thinning drugs to prevent dangerous blood clots, or thrombosis. The team’s work was published in Advanced Materials. When blood clots disrupt the flow of blood throughout the body, […]

Filed Under: Drug-Device Combinations, Featured, Pharmaceuticals, Research & Development Tagged With: North Carolina State University, University of North Carolina at Chapel Hill

Tests to begin for HIV therapy injections, long-acting implants

November 29, 2016 By Sarah Faulkner

Drugs from companies, such as GlaxoSmithKline (NYSE:GSK), Gilead Sciences (NSDQ:GILD) and Merck (NYSE:MRK), are reportedly being considered for large-scale trials evaluating injectable HIV prevention therapies. Eventually, researchers hope to produce matchstick-sized implants that could provide year-long protection to vulnerable populations. Foster City, Calif.-based Gilead has a once-daily pill, Truvada, which prevents HIV infection during sex. Pre-exposure prophylaxis, also known […]

Filed Under: Drug-Device Combinations, Featured, Implants, Preclinical Trials, Research & Development Tagged With: Gilead Sciences, GlaxoSmithKline plc, Merck

Researchers develop bioresorbable capsule for treating hemophilia

November 28, 2016 By Sarah Faulkner

Researchers develop bioresorbable capsule for treating hemophilia

Researchers from the Cockrell School of Engineering at the University of Texas at Austin have developed a biodegradable capsule to deliver a protein therapy for hemophilia. The research, published in the International Journal of Pharmaceutics, could provide a cheaper, less painful alternative to injections or infusions. The capsule contains micro and nanoparticles which carry a protein […]

Filed Under: Drug-Device Combinations, Featured, Nanoparticles, Research & Development Tagged With: University of Texas at Austin

Engineered sugar clusters could enable targeted drug delivery

November 28, 2016 By Sarah Faulkner

Researchers have developed a method to engineer sugar clusters attached to proteins or lipids, called glycan complexes, to target particular organs of the body. A team from the Riken Biofunctional Synthetic Chemistry Laboratory in Japan and Kazan Federal University in Russia published their work in Advanced Science. The engineered sugar clusters could lead to glycocluster-based diagnostic tools with […]

Filed Under: Featured, Oncology, Research & Development

Researchers develop human lung model

November 28, 2016 By Sarah Faulkner

(Reuters) – Czech scientists have developed a model of a functioning human lung that can be used to simulate problems like asthma or other chronic diseases and their treatments. The research group from the Brno University of Technology says its mechanical- and computer-based model of the lung can help devise treatment methods with more precision […]

Filed Under: Featured, Pharmaceuticals, Research & Development, Respiratory

Supersonic spray produces nanomaterials for wearable electronics

November 23, 2016 By Sarah Faulkner

Supersonic spray produces nanomaterials for wearable electronics

Researchers from the University of Illinois at Chicago and Korea University have developed an ultrathin, highly conductive nanomaterial produced by a supersonic spray, according to the study published in Advanced Functional Materials. The bendable, stretchable film could be used to develop wearable electronics. The film is composed of fused silver nanowires, made by spraying nanowire particles through […]

Filed Under: Featured, Materials Testing, Nanoparticles, Research & Development Tagged With: Korea University, University of Illinois at Chicago

Topical immunotherapy combo effective against early skin cancer

November 22, 2016 By Sarah Faulkner

Calcipotriol, 5-fluorouracil-1x1

Researchers from the Washington University School of Medicine and Harvard Medical School have shown that a combination of 2 topical drugs can trigger an immune response against precancerous skin lesions. The study was published yesterday in The Journal of Clinical Investigation. The 2 drugs, calcipotriol and 5-fluorouracil, have been in use for years – topical 5-fluorouracil is […]

Filed Under: Featured, Immunotherapy, Oncology, Pharmaceuticals, Research & Development Tagged With: Harvard University, Washington University School of Medicine

Ivenix CEO Randle looks to reboot the infusion pump

November 22, 2016 By Sarah Faulkner

Ivenix pulls down $10m tranche in $50m round

Ivenix CEO Stuart Randle began his foray into drug pump delivery systems at Baxter in 1988, when he led the company’s effort to develop the 1st needle-free IV system. More than 20 years later, when he was approached about the corner office at Ivenix, Randle revisited the infusion pump industry and saw that the technology had not kept up […]

Filed Under: Drug-Device Combinations, Featured, Food & Drug Administration (FDA), Hospital Care, Research & Development Tagged With: Baxter International, Becton Dickinson, CareFusion, Hospira Inc., Ivenix

Novartis backs off from 2016 date for testing Google autofocus lens

November 21, 2016 By Sarah Faulkner

Novartis eyes Alcon sale

Novartis (NYSE:NVS) is reportedly backing off a 2016 start date to test its autofocusing contact lens in clinical trials, but it told Reuters that the product is “progressing steadily” in its collaboration with Google (NSDQ:GOOGL). In 2014, CEO Joe Jimenez said he hoped the lens would be on the market in 5 years and last year he said his […]

Filed Under: Clinical Trials, Featured, Optical/Ophthalmic, Research & Development Tagged With: Google, Novartis

Artificial pancreas deemed safe for hospitalized patient use

November 21, 2016 By Sarah Faulkner

Artificial pancreas

U.K. researchers have reportedly demonstrated the safety and efficacy of the artificial pancreas in Type II diabetes patients in a general hospital ward. The team’s work was published in The Lancet Diabetes & Endocrinology.  The closed-loop insulin delivery system can monitor blood sugar levels and change the insulin delivery rate accordingly, without the need for skin-pricks and […]

Filed Under: Diabetes, Drug-Device Combinations, Featured, Research & Development Tagged With: University of Cambridge Metabolic Research Laboratories

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