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Georgia Institute of Technology

Study: Microneedle patch, protein combo could boost efficacy of flu vaccine

July 20, 2017 By Sarah Faulkner

Researchers at Georgia State University and Georgia Institute of Technology have devised a method to boost the efficacy of a traditional influenza vaccine. The team combined a fusion protein into a microneedle patch made from a biocompatible polymer. The patch’s needles are biodegradable, releasing vaccine into the skin as they dissolve. Mice receiving a conventional […]

Filed Under: Drug-Device Combinations, Featured, Pharmaceuticals, Preclinical Trials, Research & Development Tagged With: Georgia Institute of Technology, georgiastateuniversity

Dissolvable microneedle patch for flu vaccine succeeds in Phase I

June 28, 2017 By Sarah Faulkner

Dissolvable microneedle patches that deliver the flu vaccine could provide a safe and cost-effective alternative to traditional immunization methods, according to the results from a Phase I trial published in The Lancet this week. The study enrolled adults ages 18 to 49 and randomly assigned them to receive a single dose of inactivated flu vaccine via […]

Filed Under: Clinical Trials, Drug-Device Combinations, Featured, Pharmaceuticals, Research & Development Tagged With: emoryuniversity, Georgia Institute of Technology

Magnets, nanoparticles open and close blood vessels for targeted drug delivery

June 9, 2017 By Sarah Faulkner

Magnets for targeted drug delivery - Rice University team

Tightly-packed endothelial cells line blood vessels and maintain a highly structured barrier. But researchers from Rice University, Emory University and the Georgia Institute of Technology have found a way to selectively create “leaky” blood vessels for targeted drug delivery. The team’s study, which was published in Nature Communications, reported that magnets can help lead iron-oxide nanoparticles […]

Filed Under: Drug-Device Combinations, Featured, Nanoparticles, Pharmaceuticals, Research & Development Tagged With: emoryuniversity, Georgia Institute of Technology, Rice University

Hydrogel tech boosts success of transplanted insulin-producing cells

June 5, 2017 By Sarah Faulkner

Hydrogel w/ pancreatic islet cells

A hydrogel material embedded with a protein to improve blood vessel growth may boost the success rate of transplanting insulin-producing islet cells into patients with Type I diabetes, according to a preclinical study published in the journal Science Advances.  In the newly-published work, supported by the National Institutes of Health and the Juvenile Diabetes Research Foundation, […]

Filed Under: Diabetes, Featured, Preclinical Trials, Research & Development Tagged With: Georgia Institute of Technology

Researchers stunt growth of ovarian cancer with nanohydrogels

November 7, 2016 By Sarah Faulkner

Researchers stunt growth of ovarian cancer with nanohydrogels

Researchers at the Georgia Institute of Technology have developed a targeted therapy using nanohydrogels to stunt the growth of ovarian tumors in in vivo tests in mice, according to a new study. The nanohydrogel is a gel pellet that researchers can load with RNA to carry into cancer cells and knock down a particular protein. “The dramatic […]

Filed Under: Featured, Hydrogels, Nanoparticles, Oncology, Research & Development, Women's Health Tagged With: Georgia Institute of Technology

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