GlaxoSmithKline (NYSE:GSK) and Innoviva (NSDQ:INVA) said today that GSK filed a regulatory submission with the FDA for the once-daily, closed triple combination therapy fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI) for patients with chronic obstructive pulmonary disease. The triple-combo therapy includes 3 drugs: fluticasone furoate, an inhaled corticosteroid; umeclidinium, a long-acting muscarinic antagonist; vilanterol, a long-acting beta2-adrenergic agonist. The medicines […]
Artificial pancreas deemed safe for hospitalized patient use
U.K. researchers have reportedly demonstrated the safety and efficacy of the artificial pancreas in Type II diabetes patients in a general hospital ward. The team’s work was published in The Lancet Diabetes & Endocrinology. The closed-loop insulin delivery system can monitor blood sugar levels and change the insulin delivery rate accordingly, without the need for skin-pricks and […]
OrbusNeich launches Combo Plus stent
OrbusNeich said today that it launched the latest version of its dual-therapy stent, the Combo Plus, featuring an antibody biological coating designed to promote vessel healing in patients with complex coronary artery disease. After the stent is implanted, the biological coating captures endothelial progenitor cells and kicks off formation of an endothelial layer. A coating of bioabsorbable polymer […]
Intarcia seeks FDA nod for 1st drug to use Medici drug delivery system
Intarcia Therapeutics said today that it submitted a New Drug Application to the FDA for its injection-free ITCA 650 candidate, the 1st drug to use Intarcia’s Medici drug delivery system to treat Type II diabetes. The ITCA 650 enables subcutaneous delivery of exenatide using a match-sized osmotic pump placed under the skin in an in-office procedure. With […]
Restoring blood vessels to tumor cells aids delivery of chemotherapy
Researchers from the Flanders Institute for Biotechnology in Belgium say they have found a way to repair dysfunctional blood vessels which allow cancer cells to escape from the blood stream and reach other organs, and which play a vital role in cancer metastasis. In a study published in Cancer Cell, researchers describe how they manipulated the blood […]
Athenex, Lilly ink clinical collaboration for 1st oral formulation of paclitaxel
Athenex said today that it inked a clinical collaboration deal to conduct a phase Ib study for its oral form of paclitaxel, Oraxol, with Eli Lilly‘s (NYSE:LLY) vascular endothelial growth factor (VEGF) receptor 2 antagonist, Cyramza. Patients with advanced gastric and esophageal cancer will be enrolled in 2017 at sites in the U.S. and Asia, where […]
Philips launches next-gen radiation dose management software
Royal Philips (NYSE:PHG) said today that it launched its 2nd generation DoseWise radiation dose management software platform for healthcare professionals to record and track radiation exposure in both patients and clinicians. The Dutch conglomerate said it’s 2nd generation version of DoseWise Portal has enhanced connectivity and informatics capabilities to help radiology departments address problems like […]
Mallinckrodt touts data for Ofirmev injected acetaminophen
Mallinckrodt Pharmaceuticals (NYSE:MNK) today released results from a clinical pharmacokinetic study evaluating the effect of IV morphine on the absorption of oral acetaminophen, touting the effectiveness of its Ofirmev IV administered acetaminophen over orally administered acetaminophen in adjunct to IV morphine. The results were presented at this year’s Pain Medicine Meeting of the American Society of […]
PixarBio raises $7m for non-addictive morphine alternative
PixarBio (OTC:PXRB) raised $7 million for its biomaterial-based opioid alternative for post-operative acute and chronic pain relief, about 18% of its $40 million equity financing according to a regulatory filing that the Medford, Mass.-based company filed yesterday. The company’s drug delivery product, NeuroRelease, is an injectable morphine replacement therapy for use in the surgical/hospital setting, the […]
Report finds pressure from Congress does not budge drug prices
Committees in Congress have issued more than a dozen subpoenas to drug-makers for alleged price-hiking in the last 2 years, with members of the House and Senate collecting hundreds of thousands of documents on pricing strategies and marketing tactics. They’ve put pharmaceutical execs through more than 16 hours of public testimony. But an Associated Press review shows that pressure from Washington […]