Vaxess Technologies said today that it won 2 grants from the Bill & Melinda Gates Foundation totalling up to $6 million for the development of inactivated polio and live attenuated measles rubella vaccines using the company’s Mimix sustained-release microneedle patch technology. The company’s Mimix technology is designed for sustained, transdermal delivery of vaccines and inmmunotherapies, […]
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Mast Therapeutics subsidiary advances trial for inhaled sodium nitrite solution
Mast Therapeutics (NYSE:MSTX) said today that its subsidiary Aires Pharmaceuticals inked a deal with the University of Pittsburgh related to its phase 1/2 open-label proof-of-concept trial for the company’s AIR001 inhaled sodium nitrite solution in patients with cystic fibrosis. The study will evaluate the nebulized drug as a treatment of Pseudomonas aeruginosa infection in CF […]
Study evaluates drug-device combo therapy for deep vein thrombosis
A National Institutes of Health-sponsored study found that most patients with deep vein thrombosis should be treated with anticoagulant drugs alone, without a procedure-based intervention. However, the same study showed that a minimally-invasive catheter-director therapy, pharmacomechanical catheter-directed thrombolysis, provided greater initial pain relief and could prevent disability in DVT patients. The research was presented today […]
Cerveau Technologies, Wisconsin Alzheimer’s Center ink research deal
Cerveau Technologies said today that it landed a clinical research agreement with the University of Wisconsin-Madison Alzheimer’s Research Center to study an early stage imaging agent with positron emission tomography scans to assess the status and progression of neurofibrillary tangles in the brain. Neurofibrillary tangles composed of tau protein are characteristic of certain neurodegenerative diseases, […]
DNA motors could power molecular machines for drug delivery
Researchers from the University of Alberta have developed nanomachines powered by synthetic DNA motors to improve disease detection and drug delivery. The team’s work was published this week in Nature Communications. The scientists developed the nanomachine using compartments composed of DNA enzyme molecules and substrates. “This nanomachine has the required fuels, DNA tracks, and a molecular switch,” […]
Study: Localized delivery of chemo improves prognosis of recurrent glioblastoma
Researchers from Amrita University in India demonstrated that localized and sustained delivery of a chemotherapeutic agent in brain tumors can improve the prognosis of recurrent glioblastoma. The team’s work was published in Scientific Reports. Although new drugs have been developed for glioblastoma multiforme, the overall survival rate for patients remains dismally low at 12 months, with […]
InGeneron raises $20m in Series D for regenerative stem cell therapies
InGeneron said today that healthcare provider Sanford Health invested $20 million in the company’s Series D financing round. The Houston, Texas.-based company said the funding will be used to support the clinical programs for its stem cell injections in patients with rotator cuff and venous ulcer tears. “This significant investment demonstrates Sanford’s commitment to be […]
AcelRx gains on Q4 earnings
Shares in AcelRx Pharmaceuticals (NSDQ:ACRX) rose today after the pharmaceutical company met expectations on Wall Street with its 4th quarter results. The Redwood City, Calif.-based company pared its losses to -$9.7 million, or -21¢ per share, on sales of $6.4 million for the 3 months ended Dec. 31, for bottom-line growth of 8.2% on sales growth of […]
Study: Growing concern over narcotic painkillers and their addiction risk
More than 50% of Americans have been prescribed narcotic painkillers, according to a Truven Health Analytics-NPR Health poll, and more than one third of respondents were concerned about painkillers’ addiction risk, effectiveness and side effects. The concern towards prescription painkillers differed between those who have been prescribed narcotic pain-relievers and those who have not. Just over […]
Researchers develop micropump for patients with glaucoma
Researchers from the University of Southern California’s Roski Eye Institute developed a micropump that can be implanted directly into the eye and deliver a predetermined dose of the diabetic macular edema drug ranibizumab. Current treatments for glaucoma are traditionally delivered using eye drops. But studies show that some patients stop taking their prescription glaucoma eye […]