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Massachusetts Institute of Technology

Researchers develop wearable patch for painless drug delivery through the skin

April 21, 2023 By Sean Whooley

MIT Ultrasound Patch for drug delivery

Researchers at MIT hope to address the difficulties of transdermal drug delivery through a new wearable patch. The MIT team sees the skin as an appealing route for drug delivery. It enables the drugs to travel directly to the necessary site, which offers benefits in wound care, pain relief and more. However, the tough outer […]

Filed Under: Clinical Trials, Drug-Device Combinations, Featured, Research & Development, Technology Tagged With: Drug delivery, Massachusetts Institute of Technology, mit, wearables

This robotic capsule could deliver large-protein drugs like insulin

September 28, 2022 By Sean Whooley

MIT Robot Drug Delivery

Researchers at the Massachusetts Institute of Technology (MIT) developed a new drug capsule with a robotic cap for improved drug delivery. Large-protein drugs generally can’t pass through the mucus barrier that lines the digestive tract. Insulin and most other “biologic drugs” with proteins or nucleic acids thus must be injected or administered in a hospital, […]

Filed Under: Diabetes, Drug-Device Combinations, Featured, Pharmaceuticals, Research & Development, Technology Tagged With: Diabetes, insulin, Massachusetts Institute of Technology, robotics

MIT researchers think microparticles could deliver ‘self-boosting’ vaccines

July 19, 2022 By Sean Whooley

MIT Self Boosting Vaccine

MIT researchers are touting microparticles that can deliver payloads at different points, potentially creating “self-boosting” vaccines. A new study, highlighted on the institute’s news website, demonstrates a way in which researchers could design vaccines that would need to be given just once before they “self-boost,” or essentially re-deliver the therapeutic, at a specified point in […]

Filed Under: Drug-Device Combinations, Nanoparticles, Pharmaceuticals, Research & Development Tagged With: Massachusetts Institute of Technology, mit

MIT researchers study the best size for nanoparticles to stop internal bleeding

February 17, 2022 By Sean Whooley

MIT Nanoparticles Internal traumatic injury

MIT researchers are examining how different-sized polymer nanoparticles circulate in the body, with a goal of treating traumatic injuries. Researchers are developing injectable nanoparticles that can attract cells to help stop the bleeding at the site of an internal injury until a patient can get to a hospital for treatment. To highlight the mechanism of […]

Filed Under: Clinical Trials, Drug-Device Combinations, Featured, Nanoparticles, Preclinical Trials Tagged With: Massachusetts Institute of Technology, mit

MIT researchers think they’ve found a way to get more particles through a syringe

July 8, 2020 By Sean Whooley

Researchers at the Massachusetts Institute of Technology (MIT) are touting a computational model that could prevent microparticle clogging during injections. Microparticles, which are about the size of a grain of sand, can be difficult to inject if they get clogged in a typical syringe. The research team at MIT developed this new model that determines […]

Filed Under: Discovery, Drug-Device Combinations, Featured, Immunotherapy, Research & Development Tagged With: Massachusetts Institute of Technology

This coin-sized smart insulin patch could monitor glucose for diabetes management

February 5, 2020 By Danielle Kirsh

diabetes-patch-research

Researchers at three universities have developed a smart insulin-delivery patch that has the potential to also monitor and manage glucose levels in people with diabetes. The adhesive patch was developed by a team of researchers and bioengineers from UCLA, the University of North Carolina School of Medicine and the Massachusetts Institute of Technology. It is […]

Filed Under: Diabetes Tagged With: Massachusetts Institute of Technology, mit, UCLA, University of North Carolina

Study: Researchers develop ingestible capsule for insulin delivery

February 11, 2019 By Sarah Faulkner

A team of researchers from MIT developed an ingestible, blueberry-sized capsule that can deliver insulin orally. In animal models, the capsule lowered blood sugar levels and performed comparably with the traditional route of insulin delivery – injections. The capsule features a small needle made of freeze-dried, compressed insulin. The needle is attached to a compressed […]

Filed Under: Diabetes, Drug-Device Combinations, Featured, Pharmaceuticals, Research & Development Tagged With: Brigham & Women's Hospital, Massachusetts Institute of Technology, National Institutes of Health, Novo Nordisk

Researchers design ingestible sensor for controlled drug release

December 31, 2018 By Sarah Faulkner

MIT wireless pill

Researchers from MIT, Brigham & Women’s Hospital and Draper have developed a Bluetooth-controlled ingestible capsule that can sense the temperature of its environment and reside in the stomach for at least a month. The device, which was tested in an animal study and composed of 3D-printed parts, is powered by a small silver oxide battery […]

Filed Under: Drug-Device Combinations, Featured, Patient Monitoring, Pharmaceuticals Tagged With: Brigham & Women's Hospital, Draper, Massachusetts Institute of Technology

Researchers use microparticles for targeted delivery of brain cancer therapy

August 7, 2018 By Sarah Faulkner

MIT - Glioma therapy

A team of researchers from Brigham & Women’s Hospital, Mass. Institute of Technology and Mass. General Hospital demonstrated that localizing the delivery of NAMPT inhibitors can extend survival in a mouse model of glioma, according to a paper published this week in the Proceedings of the National Academy of Sciences. The scientists created a test to […]

Filed Under: Drug-Device Combinations, Featured, Nanoparticles, Oncology, Pharmaceuticals, Research & Development Tagged With: Brigham & Women's Hospital, Massachusetts General Hospital, Massachusetts Institute of Technology

Acorda’s CEO on failure, perseverance and the profound risks of drug development

July 25, 2018 By Sarah Faulkner

Acorda Therapeutics and CEO Ron Cohen

Dr. Ron Cohen isn’t easily deterred. The physician-turned-executive has spent decades in the biotech industry and weathered a number of setbacks – he learned in his early years at the now-defunct Advanced Tissue Sciences that to succeed, he needed resilience. “I learned that it took hundreds of millions of dollars if not billions to develop […]

Filed Under: Clinical Trials, Drug-Device Combinations, Featured, Food & Drug Administration (FDA), Neurological, Pharmaceuticals, Regulatory/Compliance, Respiratory, Wall Street Beat Tagged With: Acorda Therapeutics, Massachusetts Institute of Technology

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