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Wyss Institute

These ear tubes with liquid infused materials may improve ear infection treatment outcomes

April 6, 2023 By Sean Whooley

iTTs liquid-infused material ear infection ear tubes

A research collaboration in Boston may have uncovered a design overhaul to improve outcomes for ear tubes known as tympanostomy tubes (TTs). These TTs create an opening between the ear canal and middle ear. Their aim is to ventilate the middle ear, provide a route for fluid to drain out and allow antibiotic drops to […]

Filed Under: Drug-Device Combinations, Featured, Implants, Otolaryngology Ear, Nose & Throat, Research & Development Tagged With: Harvard University, Wyss Institute

Novartis, Harvard team up to develop immunotherapy drug-delivery systems

March 21, 2018 By Sarah Faulkner

Novartis

Novartis (NYSE:NVS), Harvard University and the Dana-Farber Cancer Institute are teaming up to develop the next generation of implantable and injectable biomaterials designed to delivery immunotherapies, the group reported today. Researchers from Harvard’s Wyss Institute for Biologically Inspired Engineering have worked for years to create systems that provide targeted, sustained delivery of immuno-oncology products. Now, Novartis […]

Filed Under: Drug-Device Combinations, Featured, Immunotherapy, Implants, Pharmaceuticals, Research & Development, Wall Street Beat Tagged With: Harvard University, Novartis, Wyss Institute

Encapsulating single cells in tunable hydrogel could boost cell therapies

November 3, 2016 By Sarah Faulkner

Encapsulating single cells in tunable hydrogel could boost cell therapies

Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University and the Harvard John A. Paulson School of Engineering and Applied Sciences have developed a microfluidic approach to trap individual cells within a hydrogel material that can be tuned to match the physiological conditions of the body, according to a study published this […]

Filed Under: Hydrogels, Research & Development Tagged With: Harvard University, Wyss Institute

Tunable hydrogel helps predict tissue response to chemotherapy

October 12, 2016 By Sarah Faulkner

Tunable polymers

Researchers from the Wyss Institute developed a hydrogel microenvironment to evaluate how physical properties like stiffness of the extracellular matrix impacts the efficacy of chemotherapy. “To have success with chemotherapy and other drug therapies, we will likely need to screen their effectiveness against cells living in various environments, and not just assume that cells will always […]

Filed Under: Featured, Oncology, Pharmaceuticals, Research & Development Tagged With: Wyss Institute

Bioprinted 3D renal architecture recapitulates kidney function

October 12, 2016 By Sarah Faulkner

Human proximal tubule cells adhere to the hollow channel, forming a functional, 3D renal architecture. Credit: Lewis Lab/Wyss Institute at Harvard University

Researchers from the Wyss Institute for Biologically Inspired Engineering at Harvard University have bioprinted a functional 3D renal architecture with living human epithelial cells. Previously, the team bioprinted tissue constructs made of living cells alongside a vascular network in an extracellular matrix. These constructs are functional in vitro for more than a month. “The current work […]

Filed Under: Featured, Regenerative Medicine, Research & Development Tagged With: Wyss Institute

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