The Novo Nordisk Foundation, the Broad Institute of MIT and Harvard have launched an initiative to gain insights into disease mechanisms. To accelerate efforts to mine genetic data for insights into mechanisms — and eventually rationally design treatments — the trio of entities launched the Novo Nordisk Foundation Center for Genomic Mechanisms of Disease based […]
Harvard University
These ‘smart’ bandages could heal chronic wounds
UConn biomedical engineers are touting a wirelessly controlled “smart” bandage and corresponding platform for delivering medications to chronic, non-healing wounds. UConn’s School of Dental Medicine, School of Medicine and School of Engineering comprise the biomedical engineering department, which contributed to developing the smart bandage. Ali Tamayol, an associate professor at UConn, led the development of […]
Researchers deliver cardiac stem cell therapy in preclinical trial using refillable patch
Researchers have developed a small device designed to halt the effects of a heart attack by delivering a stem cell therapy directly to damaged cardiac tissue. In a study published in Nature Biomedical Engineering, researchers from Harvard University, the Massachusetts Institute of Technology, the National University of Ireland Galway and Trinity College Dublin reported that the […]
Novartis, Harvard team up to develop immunotherapy drug-delivery systems
Novartis (NYSE:NVS), Harvard University and the Dana-Farber Cancer Institute are teaming up to develop the next generation of implantable and injectable biomaterials designed to delivery immunotherapies, the group reported today. Researchers from Harvard’s Wyss Institute for Biologically Inspired Engineering have worked for years to create systems that provide targeted, sustained delivery of immuno-oncology products. Now, Novartis […]
Researchers combine a smart phone, insulin pump and CGM in diabetes study
In a study published this week in Diabetes Care, researchers combined an insulin pump, a continuous glucose monitoring receiver and a smart phone with cloud-based algorithms to automatically monitor and adjust a patient’s glucose levels. The team pointed towards a number of systems that are designed to function as an artificial pancreas, but still require that […]
Smart bandage releases medication as needed
A team of researchers from the University of Nebraska, Harvard Medical School and MIT have created a smart bandage that can be loaded with antibiotics, painkillers or other drugs and triggered by a smartphone. The bandage, made of electrically conductive fibers individually coated in a drug-loaded hydrogel, could be used to deliver multiple drugs at […]
X-Biotix to address antibiotic resistance with chemical scaffolds
X-Biotix Therapeutics launched today with technology from Harvard Medical School that the company said will aim to address the threat of antibiotic resistance. According to the multi-year collaboration and license agreement, the team plans to identify antibiotic scaffolds that target multi-drug-resistant Gram-negative pathogens. X-Biotix spun out of the privately-held biotech X-Chem, which develops novel small molecule therapeutics […]
Medicaid expansion tied to increase in prescriptions for diabetes drugs, birth control
The number of prescriptions filled by adults using Medicaid rose 19% in states that expanded Medicaid compared to states that did not under the Affordable Care Act, according to a new study from the Harvard T.H. Chan School of Public Health. The largest increases were for drugs that help patients deal with chronic conditions, including […]
Study: Laser-activated gold microstructures deliver cargo directly into cells
Researchers from the Harvard University’s John A. Paulson School of Engineering and Applied Sciences have developed a method to deliver molecules into cells using gold microstructures. The team published their work in ACS Nano. Previous work has been done to deliver drugs or DNA into cells by tricking or forcing open the cell membrane, but the […]
Evotec, Celgene ink drug development deal for stem cell treatments for neurodegenerative diseases
Evotec (ETR:EVT) said today that it inked a 5-year drug discovery and development deal with Celgene (NSDQ:CELG) to identify stem cell therapies for a range of neurodegenerative diseases including amyotrophic lateral sclerosis, Alzheimer’s disease and Parkinson’s disease. According to the agreement, Hamburg, Germany-based Evotec will receive an upfront payment of $45 million and Celgene will hold exclusive […]
