A team of researchers from the Shanghai Institute of Ceramics, Chinese Academy of Sciences and the East China Normal University have developed polyvinyl pyrrolidone modified nanoparticles that serve as a deoxygenation agent against tumor cells. The therapy, which is described in Nature Nanotechnology, targeted cancer cells by cutting off the tumor’s blood supply to deprive and ‘suffocate’ […]
Nanoparticles
Cytori buys Azaya’s nanoparticle tech in stock deal
Cytori Therapeutics (NSDQ:CYTX) said this week that it bought San Antonio-based Azaya Therapeutics and its nanoparticle cancer drugs in a stock deal. Azaya shareholders will receive $2 million in CTYX stock. San Diego-based Cytori will also pay $2 million upfront for costs associated with Azaya’s new manufacturing facility in San Antonio. Cytori will acquire a […]
leon-nanodrugs, Bionpharma to develop microjet reactor-based dermatological product
leon-nanodrugs GmbH and Bionpharma Inc. said yesterday that the 2 groups inked a deal to develop a dermatological product using leon-nanodrugs’ microjet reactor nanotechnology platform. The companies will share the development of the undisclosed product. Development will be done at leon-nanodrugs’ U.S.-based formulation partner CoreRx in Clearwater, Florida. Bionpharma will market and distribute the product […]
Merrimack sells liposome injections to Ipsen for $575m
In a deal that could earn the Cambridge, Mass.-based pharmaceutical company over $1.03 billion, Merrimack Pharmaceuticals (NSDQ:MACK) said yesterday that it is selling its liposome injection cancer drugs, Onivyde and generic Doxil, to Ipsen (EPA:IPN). Merrimack is also slashing its employee headcount down to just 80 people, after laying off 22% of its 400 employees […]
Keystone Nano wins FDA nod for nanoliposome cancer treatment
Keystone Nano said today that the FDA approved its investigational new drug application for the ceramide nanoliposome as a treatment for solid tumors. The company will launch a phase I trial at 3 sites to evaluate safe dosing levels and the product’s efficacy as a cancer therapy. Ceramide is a lipid that has demonstrated efficacy in […]
Penn State researchers use immune cells to deliver cancer drugs
Researchers from the Penn State Materials Research Institute have developed a biodegradable and photoluminescent nanoparticle that are carried by immune cells to target melanoma. The team’s work was published last week in the journal Small. “The traditional way to deliver drugs to tumors is to put the drug inside some type of nanoparticle and inject those […]
Researchers develop nanodiscs to deliver personalized cancer therapy
Researchers from the University of Michigan have developed nanodiscs that deliver a customized therapeutic vaccine to treat colon and melanoma cancer in mice. The team’s work was published in Nature Materials. “We are basically educating the immune system with these nanodiscs so that immune cells can attack cancer cells in a personalized manner,” senior author James Moon said […]
Researchers use gold nanoparticles to deliver hepatitis C vaccine
Researchers at Brigham & Women’s Hospital have developed electrically activated gold nanoparticles that can bore holes into cells’ outer membranes and allow DNA, RNA and proteins to pass through carrying their cargo. The team’s work was published in Advanced Functional Materials. The team tested its technique using a DNA vaccine against hepatitis C in a mice model. […]
Researchers use nanoparticles to overcome treatment-resistant breast cancer
Researchers from the University of Cincinnati College of Medicine have developed RNA nanoparticles that show promise in overcoming treatment-resistant breast cancer. The team’s work was published in ACS Nano. The researchers used a nanocarrier to target HER2-positive breast cancer and stop the production of a specific protein to prevent metastasis and render the cancer cells vulnerable to tamoxifen, […]
Researchers develop nanorockets that respond to changing temperatures
Researchers at Radboud University have developed nanorockets with temperature responsive “brakes”, enabling the carrier to stop in diseased tissues where temperatures are higher. The team’s work was published in Nature Chemistry this week. The nanocarriers can self-assemble to form functional units in any shape. “Our biggest challenge is to provide our nanorockets with various functionalities,” senior author […]
