A team of researchers from Brigham & Women’s Hospital, Mass. Institute of Technology and Mass. General Hospital demonstrated that localizing the delivery of NAMPT inhibitors can extend survival in a mouse model of glioma, according to a paper published this week in the Proceedings of the National Academy of Sciences. The scientists created a test to […]
Researchers develop capsule to deliver a week’s worth of HIV drugs
A team of researchers from the Massachusetts Institute of Technology and Brigham & Women’s Hospital have developed a drug-delivery capsule that can deliver a week’s worth of HIV drugs in a single dose. The technology is designed to make it easier for people with HIV to deal with the strict schedule of medications they need […]
Using digital pills, researchers find patients consume fewer opioids than expected
Clinicians at Brigham and Women’s Hospital published a paper in the December issue of Anesthesia & Analgesia showing that digital pills successfully monitored patients taking opioids following an injury. To track the participants’ opioid use, researchers used etectRx‘s ID-Cap system, which includes a capsule embedded with an ingestible sensor. “As an investigational tool, the digital pill provides a […]
How slugs, snails & worms inspired Gecko Biomedical’s biocompatible sealant
The story behind Gecko Biomedical’s biocompatible sealant starts in the summer of 2009, when Boston Children’s Hospital‘s chief of cardiac surgery reached out to Jeffrey Karp about a problem he was experiencing in the operating room. Dr. Pedro del Nido told Karp, a professor of medicine at Harvard and the director of the Laboratory for […]
How etectRx’s “smart pill” aims to improve patient compliance trends
When Harry Travis first met Neil Euliano and learned about his medication adherence technology, the pharmaceutical industry was beginning to usher in the age of pricey drugs with Hepatitis C therapies that hit the market at prices like $500 or $1,000 dollars a pill. “It just so happened at the time, really expensive medications were […]
Study: 30% of T2D patients don’t start insulin therapy when recommended
Research from Brigham & Women’s Hospital, supported by Sanofi (NYSE:SNY), found that 30% of people with Type II diabetes don’t begin insulin therapy when it’s first recommended to them. On average, these patients are delaying treatment by two years, the researchers reported. The team’s work was published in the journal of Diabetic Medicine. “Unfortunately this isn’t uncommon, […]
Responsive, ingestible drug-delivery material could boost patient compliance
Researchers from the Massachusetts Institute of Technology and Brigham & Women’s Hospital have developed a novel, responsive drug-delivery material that can reside in the stomach for up to nine days. The teams work was published today in Nature Communications. “One of the biggest issues in health care is noncompliance, people simply not taking their drugs,” co-senior […]
Powering the next generation of ingestible drug delivery devices
Traditional implants in the gastrointestinal tract are meant to pass through a patient’s system, delivering a drug in short bursts or recording the health of a patient’s colon. But in recent years, scientists have sought after ultra-long lasting ingestible devices that can deliver drugs for several weeks in a patient’s GI tract. Lyndra, Inc., a start-up […]
Wireless power source could enable ingestible drug delivery devices
Researchers from the Massachusetts Institute of Technology, Brigham and Women’s Hospital and the Charles Stark Draper Laboratory have developed the means to wirelessly power electronic devices that stay in the digestive tract indefinitely. The team suggests that these devices could be used as sensors in the GI tract or carry drugs to be delivered over […]
MIT, Brigham researchers deliver strands of RNA using ultrasound
Researchers from the Massachusetts Institute of Technology and Brigham & Women’s Hospital have developed a technique to deliver strands of RNA to colon cells using bursts of ultrasound waves. The team’s technique turned down the production of a protein involved in inflammatory bowel disease in mice. The paper, which was published in Gastroenterology, described a simple […]
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