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Brigham & Women's Hospital

Responsive, ingestible drug-delivery material could boost patient compliance

July 25, 2017 By Sarah Faulkner

Researchers from the Massachusetts Institute of Technology and Brigham & Women’s Hospital have developed a novel, responsive drug-delivery material that can reside in the stomach for up to nine days. The teams work was published today in Nature Communications.  “One of the biggest issues in health care is noncompliance, people simply not taking their drugs,” co-senior […]

Filed Under: Drug-Device Combinations, Featured, Pharmaceuticals, Research & Development Tagged With: Brigham & Women's Hospital, Massachusetts Institute of Technology

Powering the next generation of ingestible drug delivery devices

May 17, 2017 By Sarah Faulkner

Traditional implants in the gastrointestinal tract are meant to pass through a patient’s system, delivering a drug in short bursts or recording the health of a patient’s colon. But in recent years, scientists have sought after ultra-long lasting ingestible devices that can deliver drugs for several weeks in a patient’s GI tract. Lyndra, Inc., a start-up […]

Filed Under: Drug-Device Combinations, Featured, Pharmaceuticals, Research & Development Tagged With: Brigham & Women's Hospital, Draper, lyndra, Massachusetts Institute of Technology

Wireless power source could enable ingestible drug delivery devices

April 28, 2017 By Sarah Faulkner

Wireless power source for devices

Researchers from the Massachusetts Institute of Technology, Brigham and Women’s Hospital and the Charles Stark Draper Laboratory have developed the means to wirelessly power electronic devices that stay in the digestive tract indefinitely. The team suggests that these devices could be used as sensors in the GI tract or carry drugs to be delivered over […]

Filed Under: Drug-Device Combinations, Featured, Pharmaceuticals, Research & Development Tagged With: Brigham & Women's Hospital, Draper, Massachusetts Institute of Technology

MIT, Brigham researchers deliver strands of RNA using ultrasound

January 23, 2017 By Sarah Faulkner

MIT, Brigham researchers deliver strands of RNA using ultrasound

Researchers from the Massachusetts Institute of Technology and Brigham & Women’s Hospital have developed a technique to deliver strands of RNA to colon cells using bursts of ultrasound waves. The team’s technique turned down the production of a protein involved in inflammatory bowel disease in mice. The paper, which was published in Gastroenterology, described a simple […]

Filed Under: Featured, Research & Development Tagged With: Brigham & Women's Hospital, Massachusetts Institute of Technology

Researchers use gold nanoparticles to deliver hepatitis C vaccine

December 20, 2016 By Sarah Faulkner

Researchers use gold nanoparticles to deliver hepatitis C vaccine

Researchers at Brigham & Women’s Hospital have developed electrically activated gold nanoparticles that can bore holes into cells’ outer membranes and allow DNA, RNA and proteins to pass through carrying their cargo. The team’s work was published in Advanced Functional Materials. The team tested its technique using a DNA vaccine against hepatitis C in a mice model. […]

Filed Under: Featured, Immunotherapy, Nanoparticles, Research & Development Tagged With: Brigham & Women's Hospital

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