A team of researchers from the University of Melbourne have developed a method to turn particles into “building blocks” for complex nano-structures, according to a study published in Nature Nanotechnology. “Nano-objects are difficult to manipulate, as they’re too tiny to see directly by eye, far too small to hold, and often have incompatible surfaces for assembling […]
Researchers develop personalized 3D-printed vascular stents
Researchers from Northwestern University have developed a 3D-printed vascular stent that can be personalized to the patient, the school reported this week. The stents are made of a biodegradable, citric acid-based polymer that researchers could load with drugs to release slowly as the blood vessel wall heals. “Right now, the vast majority of stents are […]
Microchip imaging platform for roundworms could accelerate research
Researchers developed a microchip imaging platform to image-analyze thousands of roundworms simultaneously, according to the Cockrell School of Engineering at the University of Texas at Austin. This is the 1st large-scale, in vivo drug discovery platform using a whole animal model, the school reported. The study, published in Nature Communications, detailed a flexible, cellphone-sized chip with […]
Mylan settles EpiPen pricing probe with $465m
Mylan (NSDQ:MYL) last week agreed to pay $465 million to settle claims that it underpaid Medicaid for its EpiPen auto-injector by misclassifying the device as a generic. Last week, the Centers for Medicare & Medicaid Services said it spent $797 million on the emergency allergy treatment between 2011 and 2015, including rebates. The Canonsburg, Pa.-based company has […]
Lupin, MonoSol Rx ink licensing deal for pediatric products
Lupin Pharmaceutical (NSE:LUPIN) said last week that it inked a licensing agreement with MonoSol Rx to develop pediatric products using MonoSol’s drug-delivery technology. Warren, N.J.-based MonoSol touts its dissolvable film, PharmaFilm, as a quick-dissolving system that’s easy to administer and masked by taste. The sublingual film is designed to support pediatric populations that often have trouble swallowing […]
Report finds ethosomes as promising transdermal delivery mechanism
Ethosomes – nanocarriers loaded with ethanol – can penetrate the skin’s protective layers and deliver a variety of drugs, a review published in Current Clinical Pharmacology reported today. Transdermal delivery of drugs is touted by some researchers as promising, since it’s noninvasive and avoids any interaction with the gastrointestinal tract. Ethosomes are malleable and their […]
Ocular therapeutics company Novaliq names new CEO
Novaliq GmbH said yesterday that it named Christian Roesky as its new CEO, replacing co-founder Bernhard Günther, who will take on a new role as chief innovation officer. The Heidelberg, Germany-based company focuses on renovating poorly soluble drugs into effective ocular therapeutics. Its CE-marked product, NovaTears, was developed from its proprietary EyeSol technology. With its […]
Nanoparticles deliver engineered protein to prevent joint damage
Researchers at Washington University have developed nanoparticles to treat the inflammation that wears away at joint cartilage in patients with osteoarthritis. Traditional treatment methods to reduce inflammation involve steroid injections, but the body quickly washes them away, leaving the cells vulnerable to more inflammation. “I see a lot of patients with osteoarthritis, and there’s really […]
CMS finds Mylan overcharged Medicaid for EpiPens for years
The Centers for Medicare & Medicaid Services said this week that Mylan Pharmaceuticals (NSDQ:MYL) has been overcharging Medicaid for its EpiPen auto-injector for years, despite being warned that it should have paid bigger rebates. CMS said that between 2011 and 2015, Medicaid spent $797 million on the epinephrine auto-injector after deducting rebates, marking the 1st […]
‘Connectosomes’ efficiently deliver chemo to targeted cells
Researchers have developed a new form of nanoparticles called “connectosomes” that can efficiently deliver chemotherapy to human cells more efficiently than traditional delivery methods, according to a report out of the University of Texas at Austin. The team, who published their research in the Journal of the American Chemical Society, equipped the connectosomes with gap junctions […]