Researchers from the Massachusetts Institute of Technology and Brigham & Women’s Hospital have developed a novel, responsive drug-delivery material that can reside in the stomach for up to nine days. The teams work was published today in Nature Communications. “One of the biggest issues in health care is noncompliance, people simply not taking their drugs,” co-senior […]
Research & Development
Study: Protein ferries molecule to tumors, triggering self-destruction
Ribonucleic acids, which can alter the behavior of cancerous cells, can be effectively ferried to tumors using a human protein called albumin, according to research conducted by a team of engineers at Vanderbilt University. The team’s work could help boost treatment for patients with triple-negative breast cancer, the researchers reported in the journal Proceedings of the […]
Takeda, BioSurfaces collab on GI drug-delivery devices
Takeda Pharmaceutical (TYO:4502) and BioSurfaces said today that the two companies inked a deal to develop novel medical devices intended to treat patients with gastrointestinal diseases. The deal brings together Takeda’s experience in the gastroenterology space and BioSurfaces’ method of developing nanomaterials from FDA-approved polymers for medical implants and drug-delivery devices. Financial terms of the […]
Senseonics inks artificial pancreas deal with Roche, TypeZero Technologies
Senseonics (NYSE:SENS) said today that it inked a collaboration with TypeZero Technologies and Roche (OTC:RHHBY) Diabetes Care to develop an automated insulin delivery system. The deal is part of an NIH-funded effort to test artificial pancreas systems. The trial is slated to integrate Senseonic’s Eversense glucose monitor, TypeZero’s inControl AP algorithms and Roche’s Accu-Chek Insight insulin pump. […]
Provention Bio wants to stop Type I diabetes – with a vaccine
Before he co-founded Provention Bio, Ashleigh Palmer worked on inhaled nitric oxide for infants with respiratory failure. After the company was sold for $1.2 billion to a Baxter-led consortium, Palmer noticed there was apprehension about conducting clinical trials with neonates. He was concerned that the inhaled NO assets were slated to fall to the wayside. […]
Samumed wins orphan drug status for inhaled IPF therapy
Samumed said today that the FDA awarded orphan drug status to its inhaled idiopathic pulmonary fibrosis therapy, SMo4646. The IPF therapy is administered using a nebulizer and can be used as a montherapy or in combination with pirfenidone or nintedanib, according to the San Diego-based company. “The FDA’s decision to grant an ODD to SM04646 […]
Parkinson’s protein to take a trip into space
The Michael J. Fox Foundation for Parkinson’s Research and the Center for the Advancement of Science in Space yesterday inked a collaboration to send a protein linked to Parkinson’s disease to the International Space Station. The researchers plan to evaluate the protein’s growth under microgravity conditions, which could foster larger, more regular LRRK2 protein crystals […]
Catalent, Rutgers partner to study pediatric drug formulation and delivery
The Catalent Applied Drug Delivery Institute said today that it inked a deal to work with the dept. of pharmacy practice at Rutgers University in an effort to identify and address the challenges linked to pediatric drug formulation and delivery. The collaboration plans to focus on the development and administration of medicines to children by […]
Study: Microneedle patch, protein combo could boost efficacy of flu vaccine
Researchers at Georgia State University and Georgia Institute of Technology have devised a method to boost the efficacy of a traditional influenza vaccine. The team combined a fusion protein into a microneedle patch made from a biocompatible polymer. The patch’s needles are biodegradable, releasing vaccine into the skin as they dissolve. Mice receiving a conventional […]
Antibiotic-eluting polymer could help treat prosthetic joint infections
Researchers from Massachusetts General Hospital have developed an antibiotic-eluting polymer that could be used to treat infections in orthopedic implants, according to a report published in Nature Biomedical Engineering. Traditionally, treating a prosthetic joint infection involves removing an implant and replacing it with a temporary spacer made from antibiotic-releasing bone cement for at least six […]
