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Research & Development

How intranasal vaccines can confer immunity where it matters

March 9, 2021 By Brian Buntz

Mucosa and relevant structures

The COVID-19 vaccine landscape is gradually becoming more diverse. And it could grow more so, as several companies work on intranasal vaccines. Intranasal vaccines offer potential advantages over traditional intramuscular vaccines. They can stimulate immunoglobulin A production, which can avert infection, as a recent Scientific American article noted. Get the full story from our sister site, […]

Filed Under: Otolaryngology Ear, Nose & Throat, Pharmaceuticals, Research & Development Tagged With: COVID-19 vaccine, intranasal vaccines

Intranasal COVID-19 vaccines could be on the horizon

March 8, 2021 By Brian Buntz

Image courtesy of AltImmune

All of the COVID-19 vaccines authorized to date are delivered via intramuscular injection. But the intranasal vaccines that are now in development could lead to a more diverse vaccine landscape.  The company Altimmune (Gaithersburg, Md.) recently launched a Phase 1 clinical trial to test its single-dose adCOVID intranasal vaccine in 180 adult volunteers. Bharat Biotech […]

Filed Under: Clinical Trials, Otolaryngology Ear, Nose & Throat, Pediatrics, Pharmaceuticals, Research & Development, Respiratory Tagged With: COVID-19, intranasal, Intranasal COVID-19 vaccines

Pneumagen touts non-human results for intranasal drug treatment for COVID-19

March 8, 2021 By Sean Whooley

Pneumagen

Pneumagen announced today that study results show the effectiveness of its Neumifil intranasal drug in treating COVID-19. St. Andrews, Scotland-based Pneumagen’s Neumafil, a viral intranasal drug for protection against respiratory tract infections (RTIs), was used on a hamster model of COVID-19 infection and displayed effectiveness as it significantly reduced clinical signs and weight loss in […]

Filed Under: Clinical Trials, Drug-Device Combinations, Featured, Otolaryngology Ear, Nose & Throat, Pharmaceuticals, Research & Development, Respiratory Tagged With: coronavirus, COVID-19, Pneumagen

Pulmatrix completes $40M offering, updates product pipeline timetable

March 4, 2021 By Sean Whooley

pulmatrix

Pulmatrix (NSDQ:PULM) announced today that it completed an offering with gross proceeds of approximately $40 million. Lexington, Mass.-based Pulmatrix said in a news release that it completed the registered direct offering to extend the company’s cash runway. Now, the company has additional financing to help fully fund data readouts across its development pipeline, which includes a […]

Filed Under: Business/Financial News, Clinical Trials, Drug-Device Combinations, Featured, Food & Drug Administration (FDA), Funding Roundup, Pharmaceuticals, Research & Development Tagged With: Pulmatrix Inc.

8 drug delivery innovations you need to know

February 25, 2021 By Sean Whooley

Drug Delivery Innovations you need to know

The drug delivery space has seen plenty of innovation over the years and there are no signs of that slowing down any time soon. Improvements upon established technologies like insulin delivery devices and inhalers have been presented by some, while others have unlocked new ways of delivering drugs through a variety of means. Among the […]

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Filed Under: Auto-injectors, Business/Financial News, Clinical Trials, Diabetes, Drug-Device Combinations, Featured, Hydrogels, Otolaryngology Ear, Nose & Throat, Pharmaceuticals, Research & Development, Respiratory, Technology Tagged With: dyvebioscience, Enable Injections, evoxtherapeutics, Inovio Pharmaceuticals, Johns Hopkins, Lyra Therapeutics, Medtronic, Tandem Diabetes Care, Teva, Teva Pharmaceuticals, Teva Respiratory

Evox Therapeutics completes $95.4M Series C

February 18, 2021 By Sean Whooley

Evox Therapeutics

Evox Therapeutics announced today that it raised $95.4 million (£69.2 million) in a Series C financing round. Oxford, England-based Evox’s financing was significantly oversubscribed with high demand from both existing and new investors, according to a news release. Redmile Group led the financing while being joined by new investors OrbiMed and Invus. OrbiMed partner Chau […]

Filed Under: Business/Financial News, Featured, Funding Roundup, Pharmaceuticals, Research & Development Tagged With: Eli Lilly & Co., evoxtherapeutics, Takeda Pharmaceutical Co

Johns Hopkins researchers tout medicine-delivering microdevices

November 3, 2020 By Sean Whooley

Johns Hopkins researchers are touting microdevices that can latch onto intestinal mucosa and release drugs into the body. Led by engineering professor David Gracias and gastroenterologist Dr. Florin Selaru, the team of researchers and biomedical engineers designed and tested shape-changing microdevices that they say can mimic the way the parasitic hookworm affixes itself to an […]

Filed Under: Clinical Trials, Drug-Device Combinations, Featured, Preclinical Trials, Research & Development Tagged With: Johns Hopkins

MIT researchers think they’ve found a way to get more particles through a syringe

July 8, 2020 By Sean Whooley

Researchers at the Massachusetts Institute of Technology (MIT) are touting a computational model that could prevent microparticle clogging during injections. Microparticles, which are about the size of a grain of sand, can be difficult to inject if they get clogged in a typical syringe. The research team at MIT developed this new model that determines […]

Filed Under: Discovery, Drug-Device Combinations, Featured, Immunotherapy, Research & Development Tagged With: Massachusetts Institute of Technology

This wearable patch could treat skin cancers

June 24, 2020 By Danielle Kirsh

purdue-skin-cancer-patch

Researchers at Purdue University have developed a wearable patch that could bring an improved treatment experience to people with melanoma. Conventional melanoma therapies leave patients suffering from the toxicity and side effects of repeated treatments because of aggressive and the recurrent nature of melanoma cells, according to the researchers. The Purdue University wearable patch features […]

Filed Under: Drug-Device Combinations, Research & Development Tagged With: Purdue University

Abbott, Medtronic go head-to-head at ADA conference

June 15, 2020 By Nancy Crotti

Major medtech companies vied for the biggest news splash at this year’s annual meeting of the American Diabetes Association, announcing promising results from studies of patients who used their latest diabetes technology. The virtual 80th Annual American Diabetes Association Virtual Scientific Sessions, which runs through Tuesday, so far has featured news out of Abbott (NYSE:ABT) and Medtronic (NYSE:MDT) and several smaller […]

Filed Under: Auto-injectors, Big Data, Clinical Trials, Diabetes, Drug-Device Combinations, Featured, Patient Monitoring, Research & Development Tagged With: abbott, American Diabetes Association, Centers for Medicare and Medicaid Services (CMS), dariohealth, Medtronic, One Drop, Tandem Diabetes Care

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